HitPredict

Interactor 1: GCR (P04150)
Glucocorticoid receptor (GR) (Nuclear receptor subfamily 3 group C member 1)
Gene: NR3C1

Interactor 2: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31182584
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0006357 - regulation of transcription by RNA polymerase II GO:0019901 - protein kinase binding
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 777 Hs			1 193
+	Hs
		377225 GCR_HUMAN (1-777): 0: 933: 100.00		RHOB_HUMAN (1-191): 1.62e-73: 221: 83.94
+	Hs
		369300 ESR1_HUMAN (263-760): 1.11e-129: 400: 23.06		RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00
+	Hs
		369352 ESR1_HUMAN (263-760): 1.11e-129: 400: 23.06		RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22
+	Hs
		369284 ESR1_HUMAN (263-760): 1.11e-129: 400: 23.06		CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33
+	Hs
		369280 ESR1_HUMAN (263-760): 1.11e-129: 400: 23.06		RAC3_HUMAN (1-179): 4.85e-74: 223: 57.54
+	Hs
		120271 ESR1_HUMAN (263-760): 1.11e-129: 400: 23.06		RHOD_HUMAN (7-182): 1.68e-69: 212: 53.98
+	Hs
		587149 RXRA_HUMAN (292-759): 1.24e-123: 380: 21.14		RAC3_HUMAN (1-179): 4.85e-74: 223: 57.54
+	Hs
		925493 ESR2_HUMAN (286-769): 2.89e-107: 339: 21.34		RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22
+	Hs
		436440 ESR2_HUMAN (286-769): 2.89e-107: 339: 21.34		RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71
+	Hs
		894278 ESR2_HUMAN (286-769): 2.89e-107: 339: 21.34		CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33
+	Hs
		915878 ESR2_HUMAN (286-769): 2.89e-107: 339: 21.34		RHOB_HUMAN (1-191): 1.62e-73: 221: 83.94
+	Hs
		120570 ESR2_HUMAN (286-769): 2.89e-107: 339: 21.34		RHOD_HUMAN (7-182): 1.68e-69: 212: 53.98