HitPredict

Interactor 1: GCR (P04150)
Glucocorticoid receptor (GR) (Nuclear receptor subfamily 3 group C member 1)
Gene: NR3C1

Interactor 2: SRSF5 (Q13243)
Serine/arginine-rich splicing factor 5 (Delayed-early protein HRS) (Pre-mRNA-splicing factor SRP40) (Splicing factor, arginine/serine-rich 5)
Gene: SRSF5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	20195357
Identification Methods	display technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0016607 - nuclear speck
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 777 Hs			1 272
+	Hs
		377273 GCR_HUMAN (1-777): 0: 933: 100.00		SRSF1_HUMAN (2-170): 6.55e-57: 184: 43.68
+	Hs
		377295 GCR_HUMAN (1-777): 0: 933: 100.00		SRSF9_HUMAN (2-211): 1.47e-52: 172: 33.02
+	Hs
		377649 GCR_HUMAN (1-777): 0: 933: 100.00		RBM4_HUMAN (3-122): 5.32e-17: 81.7: 22.50
+	Hs
		369476 ESR1_HUMAN (263-760): 1.11e-129: 400: 23.06		SRSF1_HUMAN (2-170): 6.55e-57: 184: 43.68
+	Hs
		369528 ESR1_HUMAN (263-760): 1.11e-129: 400: 23.06		SRSF5_HUMAN (1-240): 2.63e-54: 178: 100.00
+	Hs
		369529 ESR1_HUMAN (263-760): 1.11e-129: 400: 23.06		SRSF6_HUMAN (5-184): 1.35e-48: 165: 61.96
+	Hs
		1028757 ESR2_HUMAN (286-769): 2.89e-107: 339: 21.34		SRSF5_HUMAN (1-240): 2.63e-54: 178: 100.00
+	Hs
		993786 ESR2_HUMAN (286-769): 2.89e-107: 339: 21.34		SRSF4_HUMAN (5-265): 3.78e-51: 176: 53.64
+	Hs
		1028586 ESR2_HUMAN (286-769): 2.89e-107: 339: 21.34		SRSF9_HUMAN (2-211): 1.47e-52: 172: 33.02
+	Hs
		370350 ESR1_HUMAN (263-760): 1.11e-129: 400: 23.06		RBM4_HUMAN (3-122): 5.32e-17: 81.7: 22.50
+	Hs
		369534 ESR1_HUMAN (263-760): 1.11e-129: 400: 23.06		PABP4_HUMAN (104-189): 3.45e-16: 80.1: 21.98
+	Hs
		369739 ESR1_HUMAN (263-760): 1.11e-129: 400: 23.06		PAP1L_HUMAN (105-189): 5.16e-16: 79.4: 16.67
+	Hs
		368886 ESR1_HUMAN (263-760): 1.11e-129: 400: 23.06		PABP1_HUMAN (98-189): 1.16e-15: 78.6: 18.56
+	Hs
		370422 ESR1_HUMAN (263-760): 1.11e-129: 400: 23.06		PABP3_HUMAN (98-189): 8.72e-15: 75.9: 18.56
+	Hs
		369064 ESR1_HUMAN (263-760): 1.11e-129: 400: 23.06		TIA1_HUMAN (2-101): 1.95e-12: 68.6: 16.67
+	Hs
		369421 ESR1_HUMAN (263-760): 1.11e-129: 400: 23.06		TIAR_HUMAN (3-103): 3.49e-12: 67.4: 14.56
+	Hs
		369401 ESR1_HUMAN (263-760): 1.11e-129: 400: 23.06		SRSF3_HUMAN (4-78): 1.85e-11: 62.8: 47.56
+	Hs
		1031409 ESR2_HUMAN (286-769): 2.89e-107: 339: 21.34		PABP4_HUMAN (104-189): 3.45e-16: 80.1: 21.98
+	Hs
		680471 ESR2_HUMAN (286-769): 2.89e-107: 339: 21.34		TIA1_HUMAN (2-101): 1.95e-12: 68.6: 16.67
+	Hs
		963552 ESR2_HUMAN (286-769): 2.89e-107: 339: 21.34		TIAR_HUMAN (3-103): 3.49e-12: 67.4: 14.56