HitPredict

Interactor 1: GCR (P04150)
Glucocorticoid receptor (GR) (Nuclear receptor subfamily 3 group C member 1)
Gene: NR3C1

Interactor 2: KCC2G (Q13555)
Calcium/calmodulin-dependent protein kinase type II subunit gamma (CaM kinase II subunit gamma) (CaMK-II subunit gamma) (EC 2.7.11.17)
Gene: CAMK2G

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	31182584, 33961781
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 777 Hs			1 558
+	Hs
		377307 GCR_HUMAN (1-777): 0: 933: 100.00		KCC2D_HUMAN (1-558): 0: 525: 64.88
+	Hs
		377305 GCR_HUMAN (1-777): 0: 933: 100.00		KCC2B_HUMAN (287-558): 1.59e-57: 205: 49.29
+	Hs
		914646 ERR3_HUMAN (282-761): 3.52e-122: 376: 26.46		KCC2G_HUMAN (1-558): 0: 672: 100.00
+	Hs
		874379 NR1H2_HUMAN (339-760): 9.43e-100: 317: 19.06		KCC2G_HUMAN (1-558): 0: 672: 100.00
+	Hs
		1039133 ESR2_HUMAN (286-769): 2.89e-107: 339: 21.34		KCC2D_HUMAN (1-558): 0: 525: 64.88
+	Hs
		369888 ESR1_HUMAN (263-760): 1.11e-129: 400: 23.06		MARK2_HUMAN (2-556): 4.99e-141: 428: 24.16
+	Hs
		1183083 ESR2_HUMAN (286-769): 2.89e-107: 339: 21.34		MARK2_HUMAN (2-556): 4.99e-141: 428: 24.16
+	Hs
		159131 ESR1_HUMAN (263-760): 1.11e-129: 400: 23.06		CSKP_HUMAN (10-308): 2.84e-83: 280: 46.08
+	Hs
		490080 NR2F6_HUMAN (401-673): 4.57e-25: 110: 29.97		KCC2A_HUMAN (1-555): 0: 550: 65.23
+	Hs
		818873 RXRG_HUMAN (297-761): 1.25e-115: 359: 20.17		KCC2B_HUMAN (287-558): 1.59e-57: 205: 49.29