HitPredict

Interactor 1: GCR (P04150)
Glucocorticoid receptor (GR) (Nuclear receptor subfamily 3 group C member 1)
Gene: NR3C1

Interactor 2: RAI1 (Q7Z5J4)
Retinoic acid-induced protein 1
Gene: RAI1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	28611094, 31182584
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 777 Hs			1 1906
+	Hs
		377783 GCR_HUMAN (1-777): 0: 933: 100.00		TCF20_HUMAN (203-1903): 0: 645: 21.29
+	Hs
		377467 GCR_HUMAN (1-777): 0: 933: 100.00		PHF6_HUMAN (1613-1903): 3.99e-41: 158: 18.40
+	Hs
		377262 GCR_HUMAN (1-777): 0: 933: 100.00		KMT2A_HUMAN (1715-1905): 1.1e-36: 155: 21.89
+	Hs
		377401 GCR_HUMAN (1-777): 0: 933: 100.00		NIPBL_HUMAN (1003-1659): 1.45e-17: 91.9: 15.09
+	Hs
		377624 GCR_HUMAN (1-777): 0: 933: 100.00		MINT_HUMAN (395-1722): 4.02e-10: 67.5: 11.33
+	Hs
		152574 GCR_HUMAN (1-777): 0: 933: 100.00		KMT2D_HUMAN (1054-1821): 3.12e-09: 64.8: 11.73
+	Mm
		587108 ESR1_MOUSE (263-760): 2.73e-126: 391: 22.51		KDM4B_MOUSE (1411-1903): 8.66e-69: 256: 16.20
+	Mm
		587107 ESR1_MOUSE (263-760): 2.73e-126: 391: 22.51		KDM4C_MOUSE (1394-1903): 3.22e-68: 253: 11.58
+	Hs
		301117 ESR1_HUMAN (263-760): 1.11e-129: 400: 23.06		KDM4B_HUMAN (1354-1903): 1.15e-62: 237: 13.31
+	Mm
		587106 ESR1_MOUSE (263-760): 2.73e-126: 391: 22.51		KDM4A_MOUSE (1398-1903): 8.11e-47: 186: 11.01
+	Hs
		369955 ESR1_HUMAN (263-760): 1.11e-129: 400: 23.06		PHF6_HUMAN (1613-1903): 3.99e-41: 158: 18.40
+	Hs
		370701 ESR1_HUMAN (263-760): 1.11e-129: 400: 23.06		KMT2B_HUMAN (1714-1905): 9.33e-38: 158: 22.80
+	Hs
		369449 ESR1_HUMAN (263-760): 1.11e-129: 400: 23.06		KMT2A_HUMAN (1715-1905): 1.1e-36: 155: 21.89
+	Hs
		369815 ESR1_HUMAN (263-760): 1.11e-129: 400: 23.06		NIPBL_HUMAN (1003-1659): 1.45e-17: 91.9: 15.09
+	Hs
		370040 ESR1_HUMAN (263-760): 1.11e-129: 400: 23.06		KMT2C_HUMAN (1551-1902): 5.03e-14: 80.6: 15.86
+	Hs
		370263 ESR1_HUMAN (263-760): 1.11e-129: 400: 23.06		MINT_HUMAN (395-1722): 4.02e-10: 67.5: 11.33
+	Hs
		152573 ESR1_HUMAN (263-760): 1.11e-129: 400: 23.06		KMT2D_HUMAN (1054-1821): 3.12e-09: 64.8: 11.73
+	Mm
		101828 ERR2_MOUSE (316-761): 1.69e-113: 352: 24.44		F8WI37_MOUSE (891-1771): 6.77e-15: 83.3: 11.04
+	Mm
		1142676 ERR2_MOUSE (316-761): 1.69e-113: 352: 24.44		KMT2C_MOUSE (891-1771): 6.71e-15: 83.3: 11.04
+	Mm
		1142660 ERR2_MOUSE (316-761): 1.69e-113: 352: 24.44		KMT2D_MOUSE (1722-1904): 5.26e-12: 73.7: 19.07