HitPredict

Interactor 1: GCR (P04150)
Glucocorticoid receptor (GR) (Nuclear receptor subfamily 3 group C member 1)
Gene: NR3C1

Interactor 2: RYR2 (Q92736)
Ryanodine receptor 2 (RYR-2) (RyR2) (hRYR-2) (Cardiac muscle ryanodine receptor) (Cardiac muscle ryanodine receptor-calcium release channel) (Type 2 ryanodine receptor)
Gene: RYR2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31182584
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane GO:0032991 - protein-containing complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 777 Hs			1 4967
+	Hs
		377091 GCR_HUMAN (1-777): 0: 933: 100.00		RYR1_HUMAN (1-4967): 0: 6993: 64.60
+	Hs
		601671 ESR2_HUMAN (286-769): 2.89e-107: 339: 21.34		RYR1_HUMAN (1-4967): 0: 6993: 64.60
+	Hs
		377325 GCR_HUMAN (1-777): 0: 933: 100.00		ITPR3_HUMAN (4713-4953): 2.11e-91: 337: 31.72
+	Hs
		377255 GCR_HUMAN (1-777): 0: 933: 100.00		HNRPU_HUMAN (1009-1391): 1.11e-82: 295: 15.61
+	Hs
		377619 GCR_HUMAN (1-777): 0: 933: 100.00		RANB9_HUMAN (1021-1404): 2.52e-68: 250: 17.88
+	Hs
		377394 GCR_HUMAN (1-777): 0: 933: 100.00		RN123_HUMAN (1084-1239): 3.29e-41: 171: 30.63
+	Hs
		369605 ESR1_HUMAN (263-760): 1.11e-129: 400: 23.06		ITPR3_HUMAN (4713-4953): 2.11e-91: 337: 31.72
+	Hs
		1055692 ESR2_HUMAN (286-769): 2.89e-107: 339: 21.34		ITPR2_HUMAN (4713-4953): 5.91e-99: 362: 31.94
+	Hs
		369417 ESR1_HUMAN (263-760): 1.11e-129: 400: 23.06		HNRPU_HUMAN (1009-1391): 1.11e-82: 295: 15.61
+	Hs
		370339 ESR1_HUMAN (263-760): 1.11e-129: 400: 23.06		HNRL1_HUMAN (965-1395): 1e-76: 278: 14.83
+	Hs
		1055765 ESR2_HUMAN (286-769): 2.89e-107: 339: 21.34		ITPR3_HUMAN (4713-4953): 2.11e-91: 337: 31.72
+	Hs
		414488 PRGR_HUMAN (232-777): 2.39e-110: 359: 40.00		HNRPU_HUMAN (1009-1391): 1.11e-82: 295: 15.61
+	Hs
		370257 ESR1_HUMAN (263-760): 1.11e-129: 400: 23.06		RANB9_HUMAN (1021-1404): 2.52e-68: 250: 17.88
+	Hs
		487945 RARA_HUMAN (316-759): 1.61e-105: 333: 19.60		HNRPU_HUMAN (1009-1391): 1.11e-82: 295: 15.61
+	Hs
		487339 ANDR_HUMAN (357-777): 2.54e-100: 332: 45.15		HNRPU_HUMAN (1009-1391): 1.11e-82: 295: 15.61
+	Hs
		487732 ANDR_HUMAN (357-777): 2.54e-100: 332: 45.15		HNRL1_HUMAN (965-1395): 1e-76: 278: 14.83
+	Hs
		611499 NR4A1_HUMAN (268-762): 5.59e-103: 331: 20.88		HNRL1_HUMAN (965-1395): 1e-76: 278: 14.83
+	Hs
		487700 ANDR_HUMAN (357-777): 2.54e-100: 332: 45.15		RANB9_HUMAN (1021-1404): 2.52e-68: 250: 17.88
+	Hs
		370106 ESR1_HUMAN (263-760): 1.11e-129: 400: 23.06		DDX1_HUMAN (1097-1232): 2.49e-17: 92.1: 26.47
+	Hs
		487620 ANDR_HUMAN (357-777): 2.54e-100: 332: 45.15		DDX1_HUMAN (1097-1232): 2.49e-17: 92.1: 26.47