HitPredict

Interactor 1: GCR (P04150)
Glucocorticoid receptor (GR) (Nuclear receptor subfamily 3 group C member 1)
Gene: NR3C1

Interactor 2: THIOM (Q99757)
Thioredoxin, mitochondrial (MTRX) (Mt-Trx) (Thioredoxin-2)
Gene: TXN2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.60	0.561

Property	Details
Experiments	19570036
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005759 - mitochondrial matrix
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 777 Hs			1 166
+	Hs
		377045 GCR_HUMAN (1-777): 0: 933: 100.00		THIO_HUMAN (61-165): 2.56e-36: 123: 35.85
+	Hs
		377332 GCR_HUMAN (1-777): 0: 933: 100.00		PDIA6_HUMAN (62-165): 2.26e-33: 123: 23.81
+	Hs
		377498 GCR_HUMAN (1-777): 0: 933: 100.00		TXND5_HUMAN (82-165): 3.12e-30: 115: 31.82
+	Hs
		369055 ESR1_HUMAN (263-760): 1.11e-129: 400: 23.06		PDIA3_HUMAN (30-163): 7.89e-34: 125: 19.57
+	Hs
		368870 ESR1_HUMAN (263-760): 1.11e-129: 400: 23.06		THIO_HUMAN (61-165): 2.56e-36: 123: 35.85
+	Hs
		369639 ESR1_HUMAN (263-760): 1.11e-129: 400: 23.06		PDIA6_HUMAN (62-165): 2.26e-33: 123: 23.81
+	Hs
		368827 ESR1_HUMAN (263-760): 1.11e-129: 400: 23.06		PDIA1_HUMAN (27-163): 6.3e-29: 112: 21.99
+	Hs
		1067778 ESR2_HUMAN (286-769): 2.89e-107: 339: 21.34		PDIA6_HUMAN (62-165): 2.26e-33: 123: 23.81
+	Hs
		495581 ESR2_HUMAN (286-769): 2.89e-107: 339: 21.34		THIO_HUMAN (61-165): 2.56e-36: 123: 35.85
+	Hs
		423315 ESR2_HUMAN (286-769): 2.89e-107: 339: 21.34		PDIA1_HUMAN (27-163): 6.3e-29: 112: 21.99
+	Hs
		487594 ANDR_HUMAN (357-777): 2.54e-100: 332: 45.15		TXND5_HUMAN (82-165): 3.12e-30: 115: 31.82
+	Hs
		423142 NR4A1_HUMAN (268-762): 5.59e-103: 331: 20.88		PDIA1_HUMAN (27-163): 6.3e-29: 112: 21.99