HitPredict

Interactor 1: PRIO (P04156)
Major prion protein (PrP) (ASCR) (PrP27-30) (PrP33-35C) (CD antigen CD230)
Gene: PRNP

Interactor 2: MAG (P20916)
Myelin-associated glycoprotein (Siglec-4a)
Gene: MAG

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	29791485
Identification Methods	affinity chromatography technology
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0045121 - membrane raft
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 253 Hs			1 626
+	Mm
		392760 PRIO_MOUSE (1-253): 1.74e-137: 388: 89.02		MAG_MOUSE (1-626): 4.06e-126: 387: 92.83
+	Hs
		377903 PRIO_HUMAN (1-253): 1.69e-164: 456: 100.00		NCAM1_HUMAN (3-626): 5.36e-85: 285: 15.93
+	Mm
		392757 PRIO_MOUSE (1-253): 1.74e-137: 388: 89.02		NCAM1_MOUSE (3-626): 6.26e-85: 289: 15.90
+	Mm
		192272 PRIO_MOUSE (1-253): 1.74e-137: 388: 89.02		NCAM2_MOUSE (329-626): 5.26e-25: 112: 12.73
+	Mm
		392756 PRIO_MOUSE (1-253): 1.74e-137: 388: 89.02		CNTN1_MOUSE (334-545): 1.11e-18: 92.6: 14.89
+	Mm
		103587 PRIO_MOUSE (1-253): 1.74e-137: 388: 89.02		G5E8G3_MOUSE (236-431): 7.02e-13: 72.4: 29.33
+	Mm
		392780 PRIO_MOUSE (1-253): 1.74e-137: 388: 89.02		Q8BG33_MOUSE (236-425): 3.63e-12: 70.1: 29.80
+	Mm
		57058 PRIO_MOUSE (1-253): 1.74e-137: 388: 89.02		A2AFG8_MOUSE (335-495): 6.85e-11: 67.8: 29.34
+	Mm
		392754 PRIO_MOUSE (1-253): 1.74e-137: 388: 89.02		L1CAM_MOUSE (335-495): 8.79e-11: 67.4: 29.34