HitPredict

Interactor 1: PRIO (P04156)
Major prion protein (PrP) (ASCR) (PrP27-30) (PrP33-35C) (CD antigen CD230)
Gene: PRNP

Interactor 2: ZO2 (Q9UDY2)
Tight junction protein ZO-2 (Tight junction protein 2) (Zona occludens protein 2) (Zonula occludens protein 2)
Gene: TJP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	29791485
Identification Methods	affinity chromatography technology
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0044325 - transmembrane transporter binding
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 253 Hs			1 1190
+	Hs
		378026 PRIO_HUMAN (1-253): 1.69e-164: 456: 100.00		DLG4_HUMAN (3-423): 2.31e-52: 199: 18.89
+	Hs
		378037 PRIO_HUMAN (1-253): 1.69e-164: 456: 100.00		DLG1_HUMAN (1-515): 2.7e-47: 185: 16.38
+	Hs
		378063 PRIO_HUMAN (1-253): 1.69e-164: 456: 100.00		DLG2_HUMAN (8-518): 4.46e-45: 178: 15.49
+	Hs
		378120 PRIO_HUMAN (1-253): 1.69e-164: 456: 100.00		DLG3_HUMAN (2-318): 5.99e-23: 107: 16.61