HitPredict

Interactor 1: LEU3 (P04173)
3-isopropylmalate dehydrogenase (3-IPM-DH) (IMDH) (EC 1.1.1.85) (Beta-IPM dehydrogenase)
Gene: LEU2

Interactor 2: WDR59 (Q03897)
Maintenance of telomere capping protein 5 (SEH-associated protein 3)
Gene: MTC5

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.50	0.457

Property	Details
Experiments	11805837
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 364 Sc			1 1148
+	Sc
		378362 LEU3_YEAST (1-364): 8.86e-148: 423: 100.00		COPB2_YEAST (2-364): 3.6e-36: 150: 11.14
+	Sc
		657079 IDH2_YEAST (2-359): 1.4e-132: 385: 27.20		COPB2_YEAST (2-364): 3.6e-36: 150: 11.14
+	Sc
		660918 IDH1_YEAST (3-362): 1.28e-127: 371: 26.10		COPB2_YEAST (2-364): 3.6e-36: 150: 11.14
+	Ce
		954055 IDH3A_CAEEL (5-362): 7.54e-141: 405: 26.59		LIN53_CAEEL (23-187): 2.27e-24: 109: 16.02
+	Hs
		282862 IDH3G_HUMAN (3-360): 8.01e-131: 381: 21.55		CIAO1_HUMAN (164-399): 2.77e-26: 113: 13.69
+	Ce
		954051 IDH3B_CAEEL (1-360): 2.23e-130: 380: 24.93		LIN53_CAEEL (23-187): 2.27e-24: 109: 16.02
+	Hs
		216003 IDH3B_HUMAN (3-362): 6.29e-134: 389: 25.00		FBXW7_HUMAN (230-532): 4.61e-19: 95: 5.83
+	Hs
		847160 IDH3G_HUMAN (3-360): 8.01e-131: 381: 21.55		FBXW7_HUMAN (230-532): 4.61e-19: 95: 5.83
+	Sc
		774640 LYS12_YEAST (3-359): 4.64e-109: 325: 30.73		COPB2_YEAST (2-364): 3.6e-36: 150: 11.14
+	Hs
		837722 IDH3A_HUMAN (3-362): 6.42e-141: 406: 25.34		WDR5_HUMAN (1-97): 8.99e-10: 63.7: 13.59
+	Hs
		822452 IDHP_HUMAN (4-364): 1.34e-119: 355: 15.73		WDR5_HUMAN (1-97): 8.99e-10: 63.7: 13.59