Interactor 1: GRAB (P04187)
Granzyme B(G,H) (EC 3.4.21.79) (CTLA-1) (Cytotoxic cell protease 1) (CCP1) (Fragmentin-2)
Gene: Gzmb

Interactor 2: CASP3 (P70677)
Caspase-3 (CASP-3) (EC 3.4.22.56) (Apopain) (Cysteine protease CPP32) (CPP-32) (LICE) (Protein Yama) (SREBP cleavage activity 1) (SCA-1) [Cleaved into: Caspase-3 subunit p17; Caspase-3 subunit p12]
Gene: CASP3

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 0.60 0.748

The method score is based on:

Property Details
Experiments 17283187, 17116752, 15280543, 15569669, 17179148, 9480818, 9174624
Identification Methods enzymatic study, protease assay
Interaction Type direct interaction, protein cleavage

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006915 - apoptotic process
GO:0070269 - pyroptotic inflammatory response
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 247
Mm

1 277
+ Hs
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Last updated: 15 Jul 2024