Interactor 1: CD8A (P01732)
T-cell surface glycoprotein CD8 alpha chain (T-lymphocyte differentiation antigen T8/Leu-2) (CD antigen CD8a)
Gene: CD8A
Interactor 2: PTPRC (P08575)
Receptor-type tyrosine-protein phosphatase C (EC 3.1.3.48) (Leukocyte common antigen) (L-CA) (T200) (CD antigen CD45)
Gene: PTPRC
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.41 | 0.90 | 0.614 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 1834739 |
| Identification Methods | fluorescent resonance energy transfer |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | V-set~fn3 |
| Common GO terms | GO:0005886 - plasma membrane GO:0007166 - cell surface receptor signaling pathway GO:0009897 - external side of plasma membrane GO:0042110 - T cell activation GO:0050852 - T cell receptor signaling pathway |
| Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 11Aug2025
