HitPredict

Interactor 1: MYCN (P04198)
N-myc proto-oncogene protein (Class E basic helix-loop-helix protein 37) (bHLHe37)
Gene: MYCN

Interactor 2: PRC2A (P48634)
Protein PRRC2A (HLA-B-associated transcript 2) (Large proline-rich protein BAT2) (Proline-rich and coiled-coil-containing protein 2A) (Protein G2)
Gene: PRRC2A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35013218
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 464 Hs			1 2157
+	Hs
		346208 MYC_HUMAN (7-463): 5.91e-69: 228: 34.16		PRC2A_HUMAN (1-2157): 4.11e-162: 555: 100.00
+	Hs
		379479 MYCN_HUMAN (1-464): 1.72e-89: 282: 100.00		PRC2B_HUMAN (1-2145): 2.51e-121: 430: 25.60
+	Hs
		346979 MYC_HUMAN (7-463): 5.91e-69: 228: 34.16		PRC2B_HUMAN (1-2145): 2.51e-121: 430: 25.60
+	Hs
		379116 MYCN_HUMAN (1-464): 1.72e-89: 282: 100.00		MAP1B_HUMAN (491-2148): 1.27e-36: 155: 8.83
+	Hs
		380026 MYCN_HUMAN (1-464): 1.72e-89: 282: 100.00		SRRM2_HUMAN (238-2035): 2.29e-34: 147: 9.83
+	Hs
		346565 MYC_HUMAN (7-463): 5.91e-69: 228: 34.16		MUC3A_HUMAN (36-2147): 1.06e-40: 168: 8.39
+	Hs
		346188 MYC_HUMAN (7-463): 5.91e-69: 228: 34.16		MAP1B_HUMAN (491-2148): 1.27e-36: 155: 8.83
+	Hs
		379663 MYCN_HUMAN (1-464): 1.72e-89: 282: 100.00		TITIN_HUMAN (25-1264): 8.01e-19: 96.8: 11.60
+	Hs
		347264 MYC_HUMAN (7-463): 5.91e-69: 228: 34.16		ANKH1_HUMAN (88-992): 9.48e-35: 148: 14.15
+	Hs
		348258 MYC_HUMAN (7-463): 5.91e-69: 228: 34.16		SRRM2_HUMAN (238-2035): 2.29e-34: 147: 9.83
+	Hs
		346613 MYC_HUMAN (7-463): 5.91e-69: 228: 34.16		ZO1_HUMAN (265-982): 3.45e-30: 133: 13.23
+	Hs
		347668 MYC_HUMAN (7-463): 5.91e-69: 228: 34.16		MINT_HUMAN (338-2157): 4.08e-29: 130: 10.26
+	Hs
		380070 MYCN_HUMAN (1-464): 1.72e-89: 282: 100.00		PRC2C_HUMAN (33-1884): 4.13e-12: 74.4: 11.13
+	Hs
		348379 MYC_HUMAN (7-463): 5.91e-69: 228: 34.16		NCOR2_HUMAN (550-2096): 1.47e-20: 102: 10.40
+	Hs
		347455 MYC_HUMAN (7-463): 5.91e-69: 228: 34.16		TITIN_HUMAN (25-1264): 8.01e-19: 96.8: 11.60
+	Hs
		346499 MYC_HUMAN (7-463): 5.91e-69: 228: 34.16		MAP1A_HUMAN (389-2155): 2.3e-14: 81.6: 8.60
+	Hs
		347505 MYC_HUMAN (7-463): 5.91e-69: 228: 34.16		PRG4_HUMAN (775-1650): 2.91e-14: 81.1: 12.40
+	Hs
		346789 MYC_HUMAN (7-463): 5.91e-69: 228: 34.16		MDC1_HUMAN (907-2156): 1.96e-13: 78.7: 10.22
+	Hs
		348352 MYC_HUMAN (7-463): 5.91e-69: 228: 34.16		PRC2C_HUMAN (33-1884): 4.13e-12: 74.4: 11.13
+	Hs
		346881 MYC_HUMAN (7-463): 5.91e-69: 228: 34.16		SPEG_HUMAN (361-711): 4.51e-09: 64.2: 20.27