HitPredict

Interactor 1: MYCN (P04198)
N-myc proto-oncogene protein (Class E basic helix-loop-helix protein 37) (bHLHe37)
Gene: MYCN

Interactor 2: FILA2 (Q5D862)
Filaggrin-2 (FLG-2) (Intermediate filament-associated and psoriasis-susceptibility protein) (Ifapsoriasin)
Gene: FLG2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35013218
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 464 Hs			1 2391
+	Hs
		379973 MYCN_HUMAN (1-464): 1.72e-89: 282: 100.00		CHD7_HUMAN (1784-2314): 2.13e-81: 302: 11.99
+	Hs
		348113 MYC_HUMAN (7-463): 5.91e-69: 228: 34.16		CHD7_HUMAN (1784-2314): 2.13e-81: 302: 11.99
+	Hs
		346302 MYC_HUMAN (7-463): 5.91e-69: 228: 34.16		NUP98_HUMAN (545-1218): 1.01e-78: 292: 14.16
+	Hs
		378907 MYCN_HUMAN (1-464): 1.72e-89: 282: 100.00		S10A9_HUMAN (1-109): 6.76e-42: 151: 30.91
+	Hs
		347038 MYC_HUMAN (7-463): 5.91e-69: 228: 34.16		S31H1_HUMAN (1546-2049): 2.13e-37: 157: 15.66
+	Hs
		346053 MYC_HUMAN (7-463): 5.91e-69: 228: 34.16		S10AB_HUMAN (2-102): 3.2e-43: 155: 39.60
+	Hs
		345696 MYC_HUMAN (7-463): 5.91e-69: 228: 34.16		S10A9_HUMAN (1-109): 6.76e-42: 151: 30.91
+	Hs
		346008 MYC_HUMAN (7-463): 5.91e-69: 228: 34.16		S10A2_HUMAN (2-91): 8.89e-40: 145: 32.22
+	Hs
		346373 MYC_HUMAN (7-463): 5.91e-69: 228: 34.16		S10AA_HUMAN (2-89): 2.76e-39: 143: 34.09
+	Hs
		345674 MYC_HUMAN (7-463): 5.91e-69: 228: 34.16		S10A8_HUMAN (1-95): 8.99e-36: 133: 29.47
+	Hs
		379579 MYCN_HUMAN (1-464): 1.72e-89: 282: 100.00		HORN_HUMAN (1590-2390): 3.13e-13: 78: 17.93
+	Hs
		146134 MYCN_HUMAN (1-464): 1.72e-89: 282: 100.00		ARI1A_HUMAN (169-1510): 1.82e-12: 75.5: 10.31
+	Hs
		345697 MYC_HUMAN (7-463): 5.91e-69: 228: 34.16		S10A6_HUMAN (4-90): 3.33e-27: 109: 31.03
+	Hs
		346095 MYC_HUMAN (7-463): 5.91e-69: 228: 34.16		NU214_HUMAN (180-979): 2.9e-17: 91.5: 14.63
+	Mm
		57756 MYC_MOUSE (5-463): 1.09e-71: 235: 33.95		ARI1A_MOUSE (122-1393): 3.68e-14: 81.3: 9.37
+	Hs
		345724 MYC_HUMAN (7-463): 5.91e-69: 228: 34.16		CO1A2_HUMAN (2134-2388): 1.29e-13: 79.4: 10.16
+	Hs
		347240 MYC_HUMAN (7-463): 5.91e-69: 228: 34.16		HORN_HUMAN (1590-2390): 3.13e-13: 78: 17.93
+	Hs
		146130 MYC_HUMAN (7-463): 5.91e-69: 228: 34.16		ARI1A_HUMAN (169-1510): 1.82e-12: 75.5: 10.31
+	Hs
		345635 MYC_HUMAN (7-463): 5.91e-69: 228: 34.16		CO3A1_HUMAN (89-814): 5.15e-12: 74: 12.04
+	Hs
		519723 MYCL_HUMAN (19-463): 1.22e-34: 134: 25.28		CTSR1_HUMAN (1604-2010): 6.69e-32: 138: 10.95