HitPredict

Interactor 1: MYCN (P04198)
N-myc proto-oncogene protein (Class E basic helix-loop-helix protein 37) (bHLHe37)
Gene: MYCN

Interactor 2: BRD7 (Q9NPI1)
Bromodomain-containing protein 7 (75 kDa bromodomain protein) (Protein CELTIX-1)
Gene: BRD7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35013218
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 464 Hs			1 651
+	Hs
		347970 MYC_HUMAN (7-463): 5.91e-69: 228: 34.16		BRD7_HUMAN (1-651): 1.84e-168: 498: 100.00
+	Hs
		379877 MYCN_HUMAN (1-464): 1.72e-89: 282: 100.00		BRD9_HUMAN (1-590): 1.05e-85: 282: 32.61
+	Hs
		380009 MYCN_HUMAN (1-464): 1.72e-89: 282: 100.00		BRPF3_HUMAN (3-537): 1.76e-54: 203: 16.33
+	Hs
		379333 MYCN_HUMAN (1-464): 1.72e-89: 282: 100.00		EP300_HUMAN (42-251): 3.1e-41: 164: 22.02
+	Hs
		346335 MYC_HUMAN (7-463): 5.91e-69: 228: 34.16		BRPF1_HUMAN (4-406): 3.3e-56: 208: 19.24
+	Hs
		346630 MYC_HUMAN (7-463): 5.91e-69: 228: 34.16		EP300_HUMAN (42-251): 3.1e-41: 164: 22.02
+	Hs
		347489 MYC_HUMAN (7-463): 5.91e-69: 228: 34.16		CBP_HUMAN (25-238): 1.58e-39: 158: 23.11
+	Hs
		347443 MYC_HUMAN (7-463): 5.91e-69: 228: 34.16		PHIP_HUMAN (115-637): 1.3e-38: 155: 12.74
+	Hs
		345919 MYC_HUMAN (7-463): 5.91e-69: 228: 34.16		TAF1_HUMAN (58-534): 1.25e-34: 143: 13.99
+	Hs
		345960 MYC_HUMAN (7-463): 5.91e-69: 228: 34.16		BRD2_HUMAN (115-424): 3.01e-33: 138: 15.39
+	Hs
		347855 MYC_HUMAN (7-463): 5.91e-69: 228: 34.16		BRD8_HUMAN (2-261): 5.61e-27: 119: 16.23
+	Hs
		348175 MYC_HUMAN (7-463): 5.91e-69: 228: 34.16		BAZ2A_HUMAN (70-240): 3.27e-19: 94.9: 22.65
+	Hs
		346644 MYC_HUMAN (7-463): 5.91e-69: 228: 34.16		BPTF_HUMAN (133-233): 1.15e-18: 93: 29.52
+	Hs
		738960 SRBP1_HUMAN (86-464): 8.15e-36: 143: 14.25		EP300_HUMAN (42-251): 3.1e-41: 164: 22.02
+	Hs
		999115 MLXPL_HUMAN (20-459): 2.62e-34: 138: 15.30		EP300_HUMAN (42-251): 3.1e-41: 164: 22.02
+	Hs
		738982 SRBP1_HUMAN (86-464): 8.15e-36: 143: 14.25		CBP_HUMAN (25-238): 1.58e-39: 158: 23.11
+	Hs
		998613 SRBP2_HUMAN (124-459): 1.17e-30: 128: 14.12		EP300_HUMAN (42-251): 3.1e-41: 164: 22.02
+	Hs
		1016089 SRBP2_HUMAN (124-459): 1.17e-30: 128: 14.12		CBP_HUMAN (25-238): 1.58e-39: 158: 23.11
+	Hs
		607813 USF1_HUMAN (184-463): 1.05e-29: 119: 17.83		EP300_HUMAN (42-251): 3.1e-41: 164: 22.02
+	Hs
		519730 MYCL_HUMAN (19-463): 1.22e-34: 134: 25.28		BRD8_HUMAN (2-261): 5.61e-27: 119: 16.23