HitPredict

Interactor 1: MAS (P04201)
Proto-oncogene Mas
Gene: MAS1

Interactor 2: TTK (P33981)
Dual specificity protein kinase TTK (EC 2.7.12.1) (Phosphotyrosine picked threonine-protein kinase) (PYT)
Gene: TTK

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	7tm_1~Pkinase
Common GO terms	GO:0008284 - positive regulation of cell population proliferation
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 325 Hs			1 857
+	Hs
		708278 CXCR4_HUMAN (35-313): 2.33e-64: 208: 16.05		TTK_HUMAN (1-857): 0: 776: 100.00
+	Hs
		708264 APJ_HUMAN (12-323): 1.28e-59: 197: 16.76		TTK_HUMAN (1-857): 0: 776: 100.00
+	Hs
		708266 OPRX_HUMAN (31-312): 1.32e-59: 196: 16.12		TTK_HUMAN (1-857): 0: 776: 100.00
+	Hs
		598922 FPR1_HUMAN (8-325): 4.3e-59: 195: 19.25		TTK_HUMAN (1-857): 0: 776: 100.00
+	Hs
		708356 LPAR4_HUMAN (37-306): 5.11e-58: 192: 23.31		TTK_HUMAN (1-857): 0: 776: 100.00
+	Hs
		708289 GPR17_HUMAN (34-295): 1.83e-46: 162: 18.53		TTK_HUMAN (1-857): 0: 776: 100.00
+	Hs
		380120 MAS_HUMAN (1-325): 3.61e-59: 194: 100.00		PKN3_HUMAN (49-854): 3.01e-144: 450: 14.95
+	Hs
		1031129 GPR17_HUMAN (34-295): 1.83e-46: 162: 18.53		M3K4_HUMAN (530-795): 2.19e-22: 105: 27.47