Interactor 1: HG2A (P04233)
HLA class II histocompatibility antigen gamma chain (HLA-DR antigens-associated invariant chain) (Ia antigen-associated invariant chain) (Ii) (CD antigen CD74) [Cleaved into: Class-II-associated invariant chain peptide (CLIP)]
Gene: CD74

Interactor 2: HG2A (P04233)
HLA class II histocompatibility antigen gamma chain (HLA-DR antigens-associated invariant chain) (Ia antigen-associated invariant chain) (Ii) (CD antigen CD74) [Cleaved into: Class-II-associated invariant chain peptide (CLIP)]
Gene: CD74

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.33 1.00 0.575

The method score is based on:

Property Details
Experiments 2391366
Identification Methods biochemical
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains MHCassoc_trimer~MHCassoc_trimer, Thyroglobulin_1~Thyroglobulin_1
Common GO terms GO:0000139 - Golgi membrane
GO:0001516 - prostaglandin biosynthetic process
GO:0001540 - amyloid-beta binding
GO:0001934 - positive regulation of protein phosphorylation
GO:0001961 - positive regulation of cytokine-mediated signaling pathway
and 78 others

more...

Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 296
Hs

1 296
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024