HitPredict

Interactor 1: HG2A (P04233)
HLA class II histocompatibility antigen gamma chain (HLA-DR antigens-associated invariant chain) (Ia antigen-associated invariant chain) (Ii) (CD antigen CD74) [Cleaved into: Class-II-associated invariant chain peptide (CLIP)]
Gene: CD74

Interactor 2: DPB1 (P04440)
HLA class II histocompatibility antigen, DP beta 1 chain (HLA class II histocompatibility antigen, DP(W4) beta chain) (MHC class II antigen DPB1)
Gene: HLA-DPB1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

The method score is based on:

Property	Details
Experiments	26186194, 30833792, 33961781
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000139 - Golgi membrane GO:0005765 - lysosomal membrane GO:0005886 - plasma membrane GO:0009986 - cell surface GO:0012507 - ER to Golgi transport vesicle membrane and 9 others more... GO:0016020 - membrane GO:0019886 - antigen processing and presentation of exogenous peptide antigen via MHC class II GO:0023026 - MHC class II protein complex binding GO:0030658 - transport vesicle membrane GO:0030666 - endocytic vesicle membrane GO:0030669 - clathrin-coated endocytic vesicle membrane GO:0032588 - trans-Golgi network membrane GO:0042613 - MHC class II protein complex GO:0098553 - lumenal side of endoplasmic reticulum membrane
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1	296
Hs

1	258

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024