Interactor 1: HG2A (P04233)
HLA class II histocompatibility antigen gamma chain (HLA-DR antigens-associated invariant chain) (Ia antigen-associated invariant chain) (Ii) (CD antigen CD74) [Cleaved into: Class-II-associated invariant chain peptide (CLIP)]
Gene: CD74

Interactor 2: CD44 (P16070)
CD44 antigen (CDw44) (Epican) (Extracellular matrix receptor III) (ECMR-III) (GP90 lymphocyte homing/adhesion receptor) (HUTCH-I) (Heparan sulfate proteoglycan) (Hermes antigen) (Hyaluronate receptor) (Phagocytic glycoprotein 1) (PGP-1) (Phagocytic glycoprotein I) (PGP-I) (CD antigen CD44)
Gene: CD44

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.58 0.60 0.595

The method score is based on:

Property Details
Experiments 27872288, 29190904
Identification Methods fluorescent resonance energy transfer, anti bait coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0004896 - cytokine receptor activity
GO:0005886 - plasma membrane
GO:0009986 - cell surface
GO:0035692 - macrophage migration inhibitory factor receptor complex
GO:0043066 - negative regulation of apoptotic process
and 5 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 296
Hs

1 742
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024