HitPredict

Interactor 1: K2C1 (P04264)
Keratin, type II cytoskeletal 1 (67 kDa cytokeratin) (Cytokeratin-1) (CK-1) (Hair alpha protein) (Keratin-1) (K1) (Type-II keratin Kb1)
Gene: KRT1

Interactor 2: EZH2 (Q15910)
Histone-lysine N-methyltransferase EZH2 (EC 2.1.1.356) (ENX-1) (Enhancer of zeste homolog 2) (Lysine N-methyltransferase 6)
Gene: EZH2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36517590
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 644 Hs			1 746
+	Hs
		213953 KRT86_HUMAN (79-558): 5.38e-84: 274: 43.69		EZH2_HUMAN (1-746): 0: 862: 100.00
+	Hs
		531579 K2C5_HUMAN (1-496): 2.32e-82: 272: 64.32		EZH2_HUMAN (1-746): 0: 862: 100.00
+	Hs
		380481 K2C6B_HUMAN (2-512): 5.16e-79: 263: 62.82		EZH2_HUMAN (1-746): 0: 862: 100.00
+	Hs
		821664 K2C6C_HUMAN (2-512): 2.69e-78: 261: 62.62		EZH2_HUMAN (1-746): 0: 862: 100.00
+	Hs
		359498 K2C6A_HUMAN (2-512): 2.12e-75: 253: 62.43		EZH2_HUMAN (1-746): 0: 862: 100.00
+	Mm
		1149762 K2C73_MOUSE (1-496): 9.05e-80: 264: 56.45		Q6AXH7_MOUSE (1-746): 0: 832: 96.41
+	Hs
		1080082 K2C1B_HUMAN (62-511): 4.84e-63: 220: 64.00		EZH2_HUMAN (1-746): 0: 862: 100.00
+	Mm
		430509 K2C4_MOUSE (1-505): 9.58e-69: 234: 60.59		Q6AXH7_MOUSE (1-746): 0: 832: 96.41