HitPredict

Interactor 1: S100B (P04271)
Protein S100-B (S-100 protein beta chain) (S-100 protein subunit beta) (S100 calcium-binding protein B)
Gene: S100B

Interactor 2: S10A6 (P06703)
Protein S100-A6 (Calcyclin) (Growth factor-inducible protein 2A9) (MLN 4) (Prolactin receptor-associated protein) (PRA) (S100 calcium-binding protein A6)
Gene: S100A6

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.77 1.00 0.880

The method score is based on:

Property Details
Experiments 29997244, 10913138, 9925766
Identification Methods fluorescent resonance energy transfer, two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains EF-hand_1~S_100, S_100~S_100
Common GO terms GO:0001726 - ruffle
GO:0005509 - calcium ion binding
GO:0005576 - extracellular region
GO:0005634 - nucleus
GO:0005737 - cytoplasm
and 7 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 92
Hs

1 90
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024