HitPredict

Interactor 1: S100B (P04271)
Protein S100-B (S-100 protein beta chain) (S-100 protein subunit beta) (S100 calcium-binding protein B)
Gene: S100B

Interactor 2: RAC1 (P63000)
Ras-related C3 botulinum toxin substrate 1 (EC 3.6.5.2) (Cell migration-inducing gene 5 protein) (Ras-like protein TC25) (p21-Rac1)
Gene: RAC1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	32814053
Identification Methods	two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0007155 - cell adhesion
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 92 Hs			1 192
+	Hs
		416397 S10A9_HUMAN (1-91): 3.59e-29: 102: 36.96		RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00
+	Hs
		416345 S10A9_HUMAN (1-91): 3.59e-29: 102: 36.96		RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19
+	Hs
		396714 S10A8_HUMAN (1-92): 4.18e-25: 91.4: 32.61		RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00
+	Hs
		416391 S10A9_HUMAN (1-91): 3.59e-29: 102: 36.96		CDC42_HUMAN (1-192): 1.4e-78: 234: 70.31
+	Hs
		661224 S10A2_HUMAN (2-90): 1.34e-29: 102: 44.94		CDC42_HUMAN (1-192): 1.4e-78: 234: 70.31
+	Hs
		396675 S10A8_HUMAN (1-92): 4.18e-25: 91.4: 32.61		RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19
+	Hs
		642929 S10A4_HUMAN (3-90): 2.3e-30: 104: 47.73		RHOA_HUMAN (5-192): 3.5e-77: 230: 57.98