HitPredict

Interactor 1: TBB4A (P04350)
Tubulin beta-4A chain (Tubulin 5 beta) (Tubulin beta-4 chain)
Gene: TUBB4A

Interactor 2: TBK1 (Q9UHD2)
Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase 1)
Gene: TBK1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	14743216
Identification Methods	tandem affinity purification
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 444 Hs			1 729
+	Hs
		428483 TBB5_HUMAN (1-429): 0: 714: 97.44		TBK1_HUMAN (1-729): 0: 564: 100.00
+	Hs
		428204 TBB5_HUMAN (1-429): 0: 714: 97.44		IKKE_HUMAN (1-716): 4.07e-146: 445: 48.33
+	Hs
		381205 TBB4A_HUMAN (1-427): 0: 709: 100.00		IKKE_HUMAN (1-716): 4.07e-146: 445: 48.33
+	Hs
		158369 TBB5_HUMAN (1-429): 0: 714: 97.44		IKKB_HUMAN (9-727): 1.01e-139: 430: 18.98
+	Hs
		158538 TBB2B_HUMAN (1-430): 0: 712: 96.74		IKKB_HUMAN (9-727): 1.01e-139: 430: 18.98
+	Hs
		158364 TBB4A_HUMAN (1-427): 0: 709: 100.00		IKKB_HUMAN (9-727): 1.01e-139: 430: 18.98
+	Hs
		167445 TBB5_HUMAN (1-429): 0: 714: 97.44		IKKA_HUMAN (9-637): 4.09e-121: 381: 21.08
+	Hs
		167440 TBB4A_HUMAN (1-427): 0: 709: 100.00		IKKA_HUMAN (9-637): 4.09e-121: 381: 21.08
+	Hs
		625344 TBB4B_HUMAN (1-427): 0: 713: 98.60		CDK2_HUMAN (6-312): 1.71e-119: 361: 20.97
+	Hs
		625420 TBB2A_HUMAN (1-430): 0: 709: 96.28		CDK2_HUMAN (6-312): 1.71e-119: 361: 20.97
+	Hs
		428367 TBB5_HUMAN (1-429): 0: 714: 97.44		MARK4_HUMAN (9-344): 1.37e-86: 290: 24.48
+	Dm
		1098170 TBB1_DROME (1-429): 0: 711: 96.27		IKKB_DROME (1-316): 1.37e-24: 111: 30.29
+	Dm
		902249 TBB2_DROME (1-430): 0: 702: 94.88		IKKB_DROME (1-316): 1.37e-24: 111: 30.29
+	Dm
		445208 TBB3_DROME (1-443): 0: 700: 88.64		IKKB_DROME (1-316): 1.37e-24: 111: 30.29