HitPredict

Interactor 1: GAL4 (P04386)
Regulatory protein GAL4
Gene: GAL4

Interactor 2: GAL4 (P04386)
Regulatory protein GAL4
Gene: GAL4

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.74 1.00 0.865

The method score is based on:

Property Details
Experiments 1557122, 28333434, 18611375
Identification Methods x-ray crystallography, protein complementation assay, pull down, molecular sieving, cosedimentation in solution
Interaction Type association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Gal4_dimer~Gal4_dimer, Zn_clus~Zn_clus
Common GO terms GO:0000431 - regulation of transcription from RNA polymerase II promoter by galactose
GO:0000435 - positive regulation of transcription from RNA polymerase II promoter by galactose
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
and 6 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 881
Sc

1 881
+ Sp
+ Sp
+ Sp
+ Sp
+ Sp
+ Sp
+ Sc
+ Sc
+ Sc
+ Sc
+ Sc
+ Sc
+ Sc
+ Sc
+ Sc
+ Sc

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Last updated: 15 Jul 2024