HitPredict

Interactor 1: G3P (P04406)
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) (EC 1.2.1.12) (Peptidyl-cysteine S-nitrosylase GAPDH) (EC 2.6.99.-)
Gene: GAPDH

Interactor 2: THIO (P10599)
Thioredoxin (Trx) (ATL-derived factor) (ADF) (Surface-associated sulphydryl protein) (SASP) (allergen Hom s Trx)
Gene: TXN

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	17353931, 32814053
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 335 Hs			1 105
+	Mm
		562129 G3P_MOUSE (4-335): 0: 589: 94.28		THIOM_MOUSE (5-105): 1.25e-33: 115: 34.95
+	At
		639317 G3PC1_ARATH (3-333): 0: 544: 67.57		TRXH1_ARATH (2-105): 1.55e-37: 124: 42.45
+	Sc
		334614 G3P3_YEAST (4-333): 0: 536: 64.85		TRX1_YEAST (1-102): 8.34e-39: 126: 47.06
+	Sc
		334616 G3P3_YEAST (4-333): 0: 536: 64.85		TRX2_YEAST (1-105): 1.08e-38: 126: 47.62
+	So
		429283 G3PB_SPIOL (1-334): 5.31e-166: 471: 45.46		TRXM_SPIOL (2-105): 1.38e-35: 120: 28.70