Interactor 1: EGFR (P04412)
Epidermal growth factor receptor (Egfr) (EC 2.7.10.1) (Drosophila relative of ERBB) (Gurken receptor) (Protein torpedo)
Gene: EGFR

Interactor 2: SPITZ (Q01083)
Protein spitz
Gene: spi

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.74 0.60 0.671

The method score is based on:

Property Details
Experiments 16459296, 20723758, unassigned4
Identification Methods pull down, x-ray crystallography, surface plasmon resonance, solid phase assay, experimental interaction detection
Interaction Type direct interaction, association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003015 - heart process
GO:0005886 - plasma membrane
GO:0007173 - epidermal growth factor receptor signaling pathway
GO:0007298 - border follicle cell migration
GO:0007391 - dorsal closure
and 16 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 1426
Dm

1 234
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024