Interactor 1: ARLY (P04424)
Argininosuccinate lyase (ASAL) (EC 4.3.2.1) (Arginosuccinase)
Gene: ASL

Interactor 2: ARLY (P04424)
Argininosuccinate lyase (ASAL) (EC 4.3.2.1) (Arginosuccinase)
Gene: ASL

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.91 1.00 0.957

The method score is based on:

Property Details
Experiments 25416956, 32296183, 9256435, 21988832, 25502805, 31515488, unassigned1304
Identification Methods two hybrid, x-ray crystallography, two hybrid array, two hybrid prey pooling approach, validated two hybrid
Interaction Type direct interaction, association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains ASL_C2~Lyase_1, Lyase_1~Lyase_1
Common GO terms GO:0000050 - urea cycle
GO:0004056 - argininosuccinate lyase activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006525 - arginine metabolic process
and 7 others

more...

Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 464
Hs

1 464
+ Sp
+ Sp
+ Sp
+ At
+ Cj
+ Cj
+ Cj
+ Sc
+ Mt
+ Sp
+ Ec
+ Cj
+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024