Interactor 1: HLAA (P04439)
HLA class I histocompatibility antigen, A alpha chain (Human leukocyte antigen A) (HLA-A)
Gene: HLA-A

Interactor 2: ERBB3 (P21860)
Receptor tyrosine-protein kinase erbB-3 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-3) (Tyrosine kinase-type cell surface receptor HER3)
Gene: ERBB3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.77 1.00 0.881

The method score is based on:

Property Details
Experiments 26186194, 24189400, 35384245, 28514442
Identification Methods affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains C1-set~Furin-like, C1-set~GF_recep_IV, C1-set~Recep_L_domain
Common GO terms GO:0005615 - extracellular space
GO:0005886 - plasma membrane
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 365
Hs

1 1342
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Rn
+ Rn

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024