HitPredict

Interactor 1: HLAA (P04439)
HLA class I histocompatibility antigen, A alpha chain (Human leukocyte antigen A) (HLA-A)
Gene: HLA-A

Interactor 2: TPSNR (Q9BX59)
Tapasin-related protein (TAPASIN-R) (TAP-binding protein-like) (TAP-binding protein-related protein) (TAPBP-R) (Tapasin-like)
Gene: TAPBPL

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	1.00	0.737

Property	Details
Experiments	36136978, 34591642
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	C1-set~C1-set, C1-set~V-set, C1-set~MHC_I, MHC_I~V-set
Common GO terms	GO:0000139 - Golgi membrane GO:0002502 - peptide antigen assembly with MHC class I protein complex GO:0005783 - endoplasmic reticulum GO:0005886 - plasma membrane GO:0042824 - MHC class I peptide loading complex and 1 others more... GO:0062061 - TAP complex binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 365 Hs			1 468
+	Hs
		69945 B1PKZ2_HUMAN (1-365): 3.88e-179: 503: 94.52		TPSNR_HUMAN (1-468): 1.27e-123: 370: 100.00
+	Hs
		354547 HLAB_HUMAN (1-362): 3.05e-157: 447: 85.64		TPSNR_HUMAN (1-468): 1.27e-123: 370: 100.00
+	Hs
		182246 HLAA_HUMAN (1-365): 1.3e-177: 499: 100.00		TPSN_HUMAN (116-428): 1.02e-39: 150: 25.65
+	Hs
		382338 HLAA_HUMAN (1-365): 1.3e-177: 499: 100.00		MUC18_HUMAN (197-404): 1.13e-33: 136: 21.56
+	Mm
		354643 HA11_MOUSE (1-364): 3.15e-160: 454: 66.21		TPSN_MOUSE (181-416): 2.06e-49: 176: 25.00
+	Hs
		382554 HLAA_HUMAN (1-365): 1.3e-177: 499: 100.00		BTNL2_HUMAN (171-463): 5.53e-25: 109: 12.62
+	Hs
		182242 HLAB_HUMAN (1-362): 3.05e-157: 447: 85.64		TPSN_HUMAN (116-428): 1.02e-39: 150: 25.65
+	Hs
		182250 HLAC_HUMAN (1-364): 2.2e-150: 430: 80.27		TPSN_HUMAN (116-428): 1.02e-39: 150: 25.65
+	Hs
		488114 HLAC_HUMAN (1-364): 2.2e-150: 430: 80.27		PVR_HUMAN (185-409): 1.83e-38: 146: 24.79
+	Hs
		570310 HLAG_HUMAN (1-338): 2.35e-151: 431: 82.84		MUC18_HUMAN (197-404): 1.13e-33: 136: 21.56
+	Hs
		488152 HLAC_HUMAN (1-364): 2.2e-150: 430: 80.27		MUC18_HUMAN (197-404): 1.13e-33: 136: 21.56
+	Hs
		382387 HLAA_HUMAN (1-365): 1.3e-177: 499: 100.00		DRB3_HUMAN (295-394): 3.21e-09: 59.8: 28.16
+	Hs
		488417 HLAC_HUMAN (1-364): 2.2e-150: 430: 80.27		BTNL2_HUMAN (171-463): 5.53e-25: 109: 12.62
+	Hs
		533174 HLAE_HUMAN (20-357): 5.1e-143: 411: 78.99		BTNL2_HUMAN (171-463): 5.53e-25: 109: 12.62
+	Hs
		570318 HLAG_HUMAN (1-338): 2.35e-151: 431: 82.84		DRB3_HUMAN (295-394): 3.21e-09: 59.8: 28.16
+	Hs
		354928 HLAG_HUMAN (1-338): 2.35e-151: 431: 82.84		DRB1_HUMAN (295-394): 4.28e-09: 59.4: 31.07
+	Hs
		488189 HLAC_HUMAN (1-364): 2.2e-150: 430: 80.27		DRB3_HUMAN (295-394): 3.21e-09: 59.8: 28.16
+	Hs
		354925 HLAC_HUMAN (1-364): 2.2e-150: 430: 80.27		DRB1_HUMAN (295-394): 4.28e-09: 59.4: 31.07
+	Hs
		533138 HLAE_HUMAN (20-357): 5.1e-143: 411: 78.99		DRB3_HUMAN (295-394): 3.21e-09: 59.8: 28.16
+	Hs
		354926 HLAE_HUMAN (20-357): 5.1e-143: 411: 78.99		DRB1_HUMAN (295-394): 4.28e-09: 59.4: 31.07