HitPredict

Interactor 1: CDK1 (P04551)
Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (Cell division control protein 2) (Cell division protein kinase 1) (p34 protein kinase)
Gene: cdc2

Interactor 2: PP11 (P13681)
Serine/threonine-protein phosphatase PP1-1 (EC 3.1.3.16)
Gene: dis2

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.78	0.60	0.685

Property	Details
Experiments	26771498, 25487150, 7957097, 16920624
Identification Methods	two hybrid, enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0010389 - regulation of G2/M transition of mitotic cell cycle GO:0031536 - positive regulation of exit from mitosis and 1 others more... GO:0051301 - cell division
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 297 Sp			1 327
+	Hs
		625180 CDK2_HUMAN (1-295): 2.31e-156: 439: 65.42		PP1G_HUMAN (4-327): 0: 572: 82.41
+	Hs
		625299 CDK2_HUMAN (1-295): 2.31e-156: 439: 65.42		PP1A_HUMAN (2-326): 0: 572: 81.40
+	Hs
		625300 CDK2_HUMAN (1-295): 2.31e-156: 439: 65.42		PP1B_HUMAN (1-327): 0: 570: 80.73
+	Mm
		926533 CDK2_MOUSE (1-295): 4.9e-147: 418: 55.98		PP1G_MOUSE (4-327): 0: 572: 82.41
+	Hs
		414790 CDK1_HUMAN (1-296): 8.91e-142: 402: 63.85		PP1G_HUMAN (4-327): 0: 572: 82.41
+	Hs
		414846 CDK1_HUMAN (1-296): 8.91e-142: 402: 63.85		PP1A_HUMAN (2-326): 0: 572: 81.40
+	Mm
		509478 CDK1_MOUSE (1-296): 3.12e-140: 398: 63.85		PP1G_MOUSE (4-327): 0: 572: 82.41
+	Hs
		905833 CDK5_HUMAN (1-296): 3.2e-136: 388: 53.20		PP1A_HUMAN (2-326): 0: 572: 81.40
+	Dm
		524602 CDK2_DROME (1-297): 2.9e-130: 374: 56.57		PP12_DROME (6-303): 0: 547: 84.90
+	Hs
		915165 CDK17_HUMAN (1-296): 1.63e-97: 298: 49.83		PP2AB_HUMAN (7-301): 2.09e-178: 497: 47.30