HitPredict

Interactor 1: CDK1 (P04551)
Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (Cell division control protein 2) (Cell division protein kinase 1) (p34 protein kinase)
Gene: cdc2

Interactor 2: CG21 (P24865)
G2/mitotic-specific cyclin cig1
Gene: cig1

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	9201720
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Cyclin_C~Pkinase, Cyclin_N~Pkinase
Common GO terms	GO:0000307 - cyclin-dependent protein kinase holoenzyme complex GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0032436 - positive regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0051301 - cell division
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 297 Sp			1 415
+	Hs
		538471 CDK2_HUMAN (1-295): 2.31e-156: 439: 65.42		CCNB1_HUMAN (5-408): 6.2e-120: 357: 26.44
+	Hs
		625350 CDK2_HUMAN (1-295): 2.31e-156: 439: 65.42		CCNA1_HUMAN (38-412): 1.2e-119: 357: 27.34
+	Hs
		538521 CDK3_HUMAN (1-294): 1.16e-148: 420: 63.61		CCNB1_HUMAN (5-408): 6.2e-120: 357: 26.44
+	Hs
		590125 CDK2_HUMAN (1-295): 2.31e-156: 439: 65.42		CCNA2_HUMAN (8-414): 7.37e-111: 334: 25.78
+	Hs
		303829 CDK2_HUMAN (1-295): 2.31e-156: 439: 65.42		CCNB2_HUMAN (3-414): 9.73e-111: 332: 26.27
+	Hs
		414711 CDK1_HUMAN (1-296): 8.91e-142: 402: 63.85		CCNB1_HUMAN (5-408): 6.2e-120: 357: 26.44
+	Hs
		414855 CDK1_HUMAN (1-296): 8.91e-142: 402: 63.85		CCNA1_HUMAN (38-412): 1.2e-119: 357: 27.34
+	Mm
		956329 CDK2_MOUSE (1-295): 4.9e-147: 418: 55.98		CCNA1_MOUSE (39-412): 3.25e-113: 339: 25.89
+	Hs
		590162 CDK3_HUMAN (1-294): 1.16e-148: 420: 63.61		CCNA2_HUMAN (8-414): 7.37e-111: 334: 25.78
+	Mm
		851183 CDK2_MOUSE (1-295): 4.9e-147: 418: 55.98		CCNA2_MOUSE (12-414): 8.48e-111: 333: 25.98
+	At
		621660 CDKA1_ARATH (1-296): 8.16e-141: 400: 62.29		CCA23_ARATH (2-415): 3.51e-115: 345: 25.58
+	Xl
		526765 CDK1A_XENLA (1-296): 6.9e-141: 400: 63.18		CCNB1_XENLA (5-408): 1.26e-113: 339: 26.04
+	Hs
		414732 CDK1_HUMAN (1-296): 8.91e-142: 402: 63.85		CCNA2_HUMAN (8-414): 7.37e-111: 334: 25.78
+	Hs
		303821 CDK1_HUMAN (1-296): 8.91e-142: 402: 63.85		CCNB2_HUMAN (3-414): 9.73e-111: 332: 26.27
+	At
		621661 CDKA1_ARATH (1-296): 8.16e-141: 400: 62.29		CCB12_ARATH (5-412): 7.28e-110: 332: 22.37
+	At
		621662 CDKA1_ARATH (1-296): 8.16e-141: 400: 62.29		CCA21_ARATH (2-415): 6.33e-108: 327: 23.94
+	At
		621643 CDKA1_ARATH (1-296): 8.16e-141: 400: 62.29		CCB11_ARATH (35-412): 1.19e-103: 315: 24.18
+	Sp
		383453 CDK1_SCHPO (1-297): 1.13e-143: 407: 100.00		CG22_SCHPO (39-411): 2.03e-98: 301: 34.64
+	At
		621653 CDKA1_ARATH (1-296): 8.16e-141: 400: 62.29		CCA22_ARATH (18-415): 2.11e-99: 304: 24.03
+	At
		48929 CDKA1_ARATH (1-296): 8.16e-141: 400: 62.29		CCA33_ARATH (119-407): 1.12e-96: 293: 29.00