HitPredict

Interactor 1: CDK1 (P04551)
Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (Cell division control protein 2) (Cell division protein kinase 1) (p34 protein kinase)
Gene: cdc2

Interactor 2: CDC18 (P41411)
Cell division control protein 18
Gene: CDC18

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.629

Property	Details
Experiments	9436991, 9177184
Identification Methods	affinity chromatography technology, enzymatic study
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005524 - ATP binding GO:0005634 - nucleus GO:0051301 - cell division
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 297 Sp			1 577
+	Hs
		625578 CDK2_HUMAN (1-295): 2.31e-156: 439: 65.42		CDC6_HUMAN (3-574): 1.44e-128: 389: 26.68
+	Mm
		292562 CDK2_MOUSE (1-295): 4.9e-147: 418: 55.98		CDC6_MOUSE (3-566): 4.16e-126: 383: 26.76
+	Hs
		415041 CDK1_HUMAN (1-296): 8.91e-142: 402: 63.85		CDC6_HUMAN (3-574): 1.44e-128: 389: 26.68
+	Hs
		625409 CDK2_HUMAN (1-295): 2.31e-156: 439: 65.42		ORC1_HUMAN (4-567): 1.13e-110: 352: 23.33
+	Hs
		414903 CDK1_HUMAN (1-296): 8.91e-142: 402: 63.85		ORC1_HUMAN (4-567): 1.13e-110: 352: 23.33
+	Xl
		724503 CDK1A_XENLA (1-296): 6.9e-141: 400: 63.18		P70049_XENLA (5-567): 5.55e-108: 345: 21.69
+	Dm
		184160 CDK1_DROME (1-297): 1.88e-137: 392: 60.61		ORC1_DROME (9-571): 5.73e-110: 351: 21.96
+	At
		287543 CDKA1_ARATH (1-296): 8.16e-141: 400: 62.29		CDC6A_ARATH (34-574): 8.37e-109: 338: 22.15
+	Dm
		184161 CDK2_DROME (1-297): 2.9e-130: 374: 56.57		ORC1_DROME (9-571): 5.73e-110: 351: 21.96
+	Sc
		339783 CDK1_YEAST (1-295): 2.97e-130: 373: 62.88		ORC1_YEAST (21-573): 7.01e-105: 338: 18.21
+	Sc
		339350 CDK1_YEAST (1-295): 2.97e-130: 373: 62.88		CDC6_YEAST (99-574): 9.83e-76: 251: 22.22