HitPredict

Interactor 1: CDK1 (P04551)
Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (Cell division control protein 2) (Cell division protein kinase 1) (p34 protein kinase)
Gene: cdc2

Interactor 2: ORC2 (Q09142)
Origin recognition complex subunit 2
Gene: ORC2

Species: Schizosaccharomyces pombe 972h-

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.67	0.60	0.636

Property	Details
Experiments	11486016, 8552194
Identification Methods	enzymatic study, two hybrid, affinity chromatography technology, pull down
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 297 Sp			1 535
+	Hs
		625410 CDK2_HUMAN (1-295): 2.31e-156: 439: 65.42		ORC2_HUMAN (94-534): 2.36e-137: 411: 27.58
+	Xl
		616666 CDK2_XENLA (1-295): 6.05e-153: 430: 64.75		Q5XGS9_XENLA (77-534): 3.19e-140: 418: 27.33
+	Xl
		724505 CDK1A_XENLA (1-296): 6.9e-141: 400: 63.18		Q5XGS9_XENLA (77-534): 3.19e-140: 418: 27.33
+	Sc
		339534 CDK1_YEAST (1-295): 2.97e-130: 373: 62.88		ORC2_YEAST (84-532): 6.18e-148: 439: 27.44
+	Dm
		618389 CDK1_DROME (1-297): 1.88e-137: 392: 60.61		ORC2_DROME (43-533): 9.17e-128: 388: 28.60
+	Dm
		618440 CDK2_DROME (1-297): 2.9e-130: 374: 56.57		ORC2_DROME (43-533): 9.17e-128: 388: 28.60