Interactor 1: ERBB2 (P04626)
Receptor tyrosine-protein kinase erbB-2 (EC 2.7.10.1) (Metastatic lymph node gene 19 protein) (MLN 19) (Proto-oncogene Neu) (Proto-oncogene c-ErbB-2) (Tyrosine kinase-type cell surface receptor HER2) (p185erbB2) (CD antigen CD340)
Gene: ERBB2

Interactor 2: DYST (Q03001)
Dystonin (230 kDa bullous pemphigoid antigen) (230/240 kDa bullous pemphigoid antigen) (Bullous pemphigoid antigen 1) (BPA) (Bullous pemphigoid antigen) (Dystonia musculorum protein) (Hemidesmosomal plaque protein)
Gene: DST

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.55 1.00 0.743

The method score is based on:

Property Details
Experiments 31980649, unassigned2173
Identification Methods two hybrid, ubiquitin reconstruction
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains CH~PK_Tyr_Ser-Thr
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0009925 - basal plasma membrane
GO:0016020 - membrane
and 1 others

more...

Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 1255
Hs

1 7570
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Last updated: 15 Jul 2024