HitPredict

Interactor 1: ERBB2 (P04626)
Receptor tyrosine-protein kinase erbB-2 (EC 2.7.10.1) (Metastatic lymph node gene 19 protein) (MLN 19) (Proto-oncogene Neu) (Proto-oncogene c-ErbB-2) (Tyrosine kinase-type cell surface receptor HER2) (p185erbB2) (CD antigen CD340)
Gene: ERBB2

Interactor 2: Q8IW90 (Q8IW90)
MTCH1 protein
Gene: MTCH1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.50	0.417

Property	Details
Experiments	25640309
Identification Methods	two hybrid array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1255 Hs			1 409
+	Hs
		384006 ERBB2_HUMAN (1-1255): 0: 1282: 100.00		MTCH1_HUMAN (24-348): 1.52e-72: 233: 99.69
+	Hs
		383524 ERBB2_HUMAN (1-1255): 0: 1282: 100.00		ADT2_HUMAN (54-377): 1.35e-71: 228: 13.76
+	Hs
		383743 ERBB2_HUMAN (1-1255): 0: 1282: 100.00		S25A3_HUMAN (181-375): 1.01e-20: 94.8: 12.69
+	Hs
		337757 EGFR_HUMAN (16-1253): 0: 1070: 48.40		ADT2_HUMAN (54-377): 1.35e-71: 228: 13.76
+	Hs
		397269 ERBB3_HUMAN (5-1254): 0: 1041: 38.55		ADT2_HUMAN (54-377): 1.35e-71: 228: 13.76
+	Hs
		339108 EGFR_HUMAN (16-1253): 0: 1070: 48.40		S2513_HUMAN (14-269): 3.93e-40: 153: 14.40
+	Hs
		338285 EGFR_HUMAN (16-1253): 0: 1070: 48.40		S25A3_HUMAN (181-375): 1.01e-20: 94.8: 12.69
+	Hs
		518250 ERBB3_HUMAN (5-1254): 0: 1041: 38.55		ADT3_HUMAN (170-378): 1.68e-26: 109: 13.95
+	Hs
		411356 INSR_HUMAN (584-1066): 2.91e-107: 371: 23.19		S25A3_HUMAN (181-375): 1.01e-20: 94.8: 12.69
+	Hs
		397233 IGF1R_HUMAN (337-633): 4.59e-20: 99.1: 22.92		ADT2_HUMAN (54-377): 1.35e-71: 228: 13.76
+	Rn
		69433 INSR_RAT (357-634): 2.53e-16: 87.2: 19.87		B0BN52_RAT (61-359): 2.79e-64: 209: 45.22
+	Rn
		544923 INSR_RAT (357-634): 2.53e-16: 87.2: 19.87		Q9EP88_RAT (51-160): 2.34e-14: 75.5: 11.82