HitPredict

Interactor 1: ERBB2 (P04626)
Receptor tyrosine-protein kinase erbB-2 (EC 2.7.10.1) (Metastatic lymph node gene 19 protein) (MLN 19) (Proto-oncogene Neu) (Proto-oncogene c-ErbB-2) (Tyrosine kinase-type cell surface receptor HER2) (p185erbB2) (CD antigen CD340)
Gene: ERBB2

Interactor 2: S39A7 (Q92504)
Zinc transporter SLC39A7 (Histidine-rich membrane protein Ke4) (Really interesting new gene 5 protein) (Solute carrier family 39 member 7) (Zrt-, Irt-like protein 7) (ZIP7)
Gene: SLC39A7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	35384245, 24189400
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0016020 - membrane
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 1255 Hs			1 469
+	Hs
		338772 EGFR_HUMAN (16-1253): 0: 1070: 48.40		S39A7_HUMAN (1-469): 2.05e-103: 318: 100.00
+	Hs
		338692 EGFR_HUMAN (16-1253): 0: 1070: 48.40		S39AB_HUMAN (129-467): 4.29e-49: 173: 15.04
+	Hs
		665637 EPHB2_HUMAN (650-1103): 2.29e-122: 406: 29.47		S39A7_HUMAN (1-469): 2.05e-103: 318: 100.00
+	Hs
		1072564 EPHA7_HUMAN (664-1030): 1.55e-121: 403: 30.61		S39A7_HUMAN (1-469): 2.05e-103: 318: 100.00
+	Hs
		872467 EPHA5_HUMAN (707-1010): 2.37e-53: 206: 37.46		S39A7_HUMAN (1-469): 2.05e-103: 318: 100.00