Interactor 1: ERBB2 (P04626)
Receptor tyrosine-protein kinase erbB-2 (EC 2.7.10.1) (Metastatic lymph node gene 19 protein) (MLN 19) (Proto-oncogene Neu) (Proto-oncogene c-ErbB-2) (Tyrosine kinase-type cell surface receptor HER2) (p185erbB2) (CD antigen CD340)
Gene: ERBB2

Interactor 2: PHB2 (Q99623)
Prohibitin-2 (B-cell receptor-associated protein BAP37) (D-prohibitin) (Repressor of estrogen receptor activity)
Gene: PHB2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.33 0.60 0.445

The method score is based on:

Property Details
Experiments 24189400
Identification Methods tandem affinity purification
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005886 - plasma membrane
GO:0043066 - negative regulation of apoptotic process
GO:0046982 - protein heterodimerization activity
Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 1255
Hs

1 299
+ Hs
+ Mm
+ Hs
+ Mm
+ Hs
+ Rn
+ Mm

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Last updated: 15 Jul 2024