HitPredict

Interactor 1: ERBB2 (P04626)
Receptor tyrosine-protein kinase erbB-2 (EC 2.7.10.1) (Metastatic lymph node gene 19 protein) (MLN 19) (Proto-oncogene Neu) (Proto-oncogene c-ErbB-2) (Tyrosine kinase-type cell surface receptor HER2) (p185erbB2) (CD antigen CD340)
Gene: ERBB2

Interactor 2: HACD3 (Q9P035)
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 (EC 4.2.1.134) (3-hydroxyacyl-CoA dehydratase 3) (HACD3) (Butyrate-induced protein 1) (B-ind1) (hB-ind1) (Protein-tyrosine phosphatase-like A domain-containing protein 1)
Gene: HACD3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.50	0.407

Property	Details
Experiments	24189400
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1255 Hs			1 362
+	Hs
		338453 EGFR_HUMAN (16-1253): 0: 1070: 48.40		TEBP_HUMAN (5-132): 4.53e-43: 148: 19.23
+	Hs
		665673 EPHB2_HUMAN (650-1103): 2.29e-122: 406: 29.47		HACD3_HUMAN (1-362): 1.85e-148: 425: 100.00
+	Hs
		411512 INSR_HUMAN (584-1066): 2.91e-107: 371: 23.19		HACD3_HUMAN (1-362): 1.85e-148: 425: 100.00
+	Rn
		88988 T2CB11_RAT (584-1066): 3.76e-104: 362: 22.98		D4ABI7_RAT (1-362): 2.92e-148: 424: 91.44
+	Hs
		435785 IGF1R_HUMAN (337-633): 4.59e-20: 99.1: 22.92		HACD3_HUMAN (1-362): 1.85e-148: 425: 100.00
+	Rn
		88987 INSR_RAT (357-634): 2.53e-16: 87.2: 19.87		D4ABI7_RAT (1-362): 2.92e-148: 424: 91.44