Interactor 1: ARAF (P04627)
Serine/threonine-protein kinase A-Raf (EC 2.7.11.1) (Proto-oncogene A-Raf)
Gene: ARAF

Interactor 2: BRAF (P28028)
Serine/threonine-protein kinase B-raf (EC 2.7.11.1) (Proto-oncogene B-Raf)
Gene: BRAF

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 27034005
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains C1_1~C1_1, C1_1~PK_Tyr_Ser-Thr, C1_1~RBD, PK_Tyr_Ser-Thr~PK_Tyr_Ser-Thr, RBD~RBD
Common GO terms GO:0000165 - MAPK cascade
GO:0004709 - MAP kinase kinase kinase activity
GO:0005524 - ATP binding
GO:0005739 - mitochondrion
GO:0005829 - cytosol
and 3 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 604
Mm

1 751
+ Hs
+ Mm
+ Hs
+ Hs
+ Gg
+ Hs
+ Hs
+ Hs
+ Xl
+ Mm
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024