Interactor 1: ARAF (P04627)
Serine/threonine-protein kinase A-Raf (EC 2.7.11.1) (Proto-oncogene A-Raf)
Gene: ARAF

Interactor 2: MK01 (P63085)
Mitogen-activated protein kinase 1 (MAP kinase 1) (MAPK 1) (EC 2.7.11.24) (ERT1) (Extracellular signal-regulated kinase 2) (ERK-2) (MAP kinase isoform p42) (p42-MAPK) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2)
Gene: Mapk1

Species: Mus musculus

Source: dip

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 7997270
Identification Methods biochemical
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains C1_1~Pkinase, PK_Tyr_Ser-Thr~Pkinase
Common GO terms GO:0000165 - MAPK cascade
GO:0005524 - ATP binding
GO:0005739 - mitochondrion
GO:0005829 - cytosol
GO:0106310 - protein serine kinase activity
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 604
Mm

1 358
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Mm
+ Mm
+ At
+ Hs
+ Hs
+ At
+ At

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024