Interactor 1: WNT1 (P04628)
Proto-oncogene Wnt-1 (Proto-oncogene Int-1 homolog)
Gene: WNT1

Interactor 2: SFRP1 (Q8N474)
Secreted frizzled-related protein 1 (FRP-1) (sFRP-1) (Secreted apoptosis-related protein 2) (SARP-2)
Gene: SFRP1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 10347172
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Fz~wnt
Common GO terms GO:0005109 - frizzled binding
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0005886 - plasma membrane
GO:0008284 - positive regulation of cell population proliferation
and 6 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 370
Hs

1 314
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024