Interactor 1: NTRK1 (P04629)
High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1-transforming tyrosine kinase protein) (Tropomyosin-related kinase A) (Tyrosine kinase receptor) (Tyrosine kinase receptor A) (Trk-A) (gp140trk) (p140-TrkA)
Gene: NTRK1

Interactor 2: TNR16 (P08138)
Tumor necrosis factor receptor superfamily member 16 (Gp80-LNGFR) (Low affinity neurotrophin receptor p75NTR) (Low-affinity nerve growth factor receptor) (NGF receptor) (Low-affinity nerve growth factor receptor p75NGFR) (Low-affinity nerve growth factor receptor p75NGR) (p75 ICD) (CD antigen CD271)
Gene: NGFR

Species: Homo sapiens

Source: dip

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.76 0.60 0.679

The method score is based on:

Property Details
Experiments 24333329, 25708205, 7836442, 7616616
Identification Methods affinity chromatography technology, fluorescence microscopy, cross-linking study, coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005886 - plasma membrane
GO:0007411 - axon guidance
GO:0009986 - cell surface
GO:0043121 - neurotrophin binding
GO:0048406 - nerve growth factor binding
and 1 others

more...

Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 796
Hs

1 427
+ Rn
+ Hs
+ Rn
+ Rn
+ Mm
+ Hs
+ Hs
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+ Hs
+ Hs
+ Hs
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+ Hs

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Last updated: 15 Jul 2024