HitPredict

Interactor 1: NTRK1 (P04629)
High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1-transforming tyrosine kinase protein) (Tropomyosin-related kinase A) (Tyrosine kinase receptor) (Tyrosine kinase receptor A) (Trk-A) (gp140trk) (p140-TrkA)
Gene: NTRK1

Interactor 2: RAGP1 (P46060)
Ran GTPase-activating protein 1 (RanGAP1)
Gene: RANGAP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	25921289
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	LRR_6~LRR_8
Common GO terms	GO:0030425 - dendrite GO:0048678 - response to axon injury
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 796 Hs			1 587
+	Hs
		384187 NTRK1_HUMAN (1-796): 0: 621: 100.00		RINI_HUMAN (1-326): 1.43e-34: 138: 15.43
+	Hs
		385341 NTRK1_HUMAN (1-796): 0: 621: 100.00		TONSL_HUMAN (40-313): 3.31e-13: 75.2: 20.71
+	Hs
		801683 DDR1_HUMAN (507-778): 1.77e-67: 242: 45.49		RAGP1_HUMAN (1-587): 5.93e-130: 394: 100.00
+	At
		794999 TMK1_ARATH (62-786): 1.64e-147: 458: 20.34		IMK2_ARATH (253-499): 2.04e-19: 94.4: 10.48
+	At
		84463 TMK1_ARATH (62-786): 1.64e-147: 458: 20.34		GSO1_ARATH (1-143): 4.6e-10: 64.7: 13.79
+	At
		1338064 TMK3_ARATH (60-784): 3.16e-145: 452: 19.98		RGI1_ARATH (276-499): 2.44e-11: 69: 12.44
+	At
		1341092 TMK3_ARATH (60-784): 3.16e-145: 452: 19.98		BAME2_ARATH (271-439): 3.29e-11: 68.6: 10.65
+	At
		84503 TMK3_ARATH (60-784): 3.16e-145: 452: 19.98		GSO1_ARATH (1-143): 4.6e-10: 64.7: 13.79
+	At
		221815 BAME1_ARATH (8-397): 6.11e-50: 191: 11.87		Y2241_ARATH (9-566): 1.21e-58: 213: 13.50
+	At
		45835 BAME1_ARATH (8-397): 6.11e-50: 191: 11.87		A0A1P8B036_ARATH (9-566): 1.98e-58: 212: 13.50
+	At
		221761 BAME1_ARATH (8-397): 6.11e-50: 191: 11.87		ERECT_ARATH (1-555): 5.98e-58: 211: 11.65
+	At
		45839 PSKR2_ARATH (18-372): 4.52e-37: 152: 10.73		A0A1P8B036_ARATH (9-566): 1.98e-58: 212: 13.50
+	At
		186954 BAME1_ARATH (8-397): 6.11e-50: 191: 11.87		BRI1_ARATH (56-410): 3.09e-37: 150: 11.14
+	At
		221817 BAME1_ARATH (8-397): 6.11e-50: 191: 11.87		BRL1_ARATH (3-338): 4.2e-35: 143: 11.89
+	At
		99004 BAME1_ARATH (8-397): 6.11e-50: 191: 11.87		RGI4_ARATH (127-439): 6.5e-24: 109: 9.61
+	At
		221790 BAME1_ARATH (8-397): 6.11e-50: 191: 11.87		BRL3_ARATH (241-538): 8.25e-13: 73.6: 11.37
+	At
		85349 BAME1_ARATH (8-397): 6.11e-50: 191: 11.87		ERL1_ARATH (5-160): 6.32e-12: 70.9: 14.20
+	At
		221789 BAME1_ARATH (8-397): 6.11e-50: 191: 11.87		RGI1_ARATH (276-499): 2.44e-11: 69: 12.44
+	At
		84459 BAME1_ARATH (8-397): 6.11e-50: 191: 11.87		GSO1_ARATH (1-143): 4.6e-10: 64.7: 13.79
+	At
		1341095 CLV1_ARATH (8-380): 1.83e-47: 184: 10.19		BAME2_ARATH (271-439): 3.29e-11: 68.6: 10.65