HitPredict

Interactor 1: NTRK1 (P04629)
High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1-transforming tyrosine kinase protein) (Tropomyosin-related kinase A) (Tyrosine kinase receptor) (Tyrosine kinase receptor A) (Trk-A) (gp140trk) (p140-TrkA)
Gene: NTRK1

Interactor 2: SMCA4 (P51532)
Transcription activator BRG1 (EC 3.6.4.-) (ATP-dependent helicase SMARCA4) (BRG1-associated factor 190A) (BAF190A) (Mitotic growth and transcription activator) (Protein BRG-1) (Protein brahma homolog 1) (SNF2-beta) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4)
Gene: SMARCA4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25921289
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0032991 - protein-containing complex
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 796 Hs			1 1647
+	Hs
		229277 NTRK1_HUMAN (1-796): 0: 621: 100.00		SMCA5_HUMAN (626-1631): 0: 835: 27.41
+	Hs
		384322 NTRK1_HUMAN (1-796): 0: 621: 100.00		SMCA1_HUMAN (639-1619): 0: 832: 28.82
+	Hs
		384854 NTRK1_HUMAN (1-796): 0: 621: 100.00		CHD4_HUMAN (482-1630): 0: 722: 23.79
+	Hs
		151370 NTRK1_HUMAN (1-796): 0: 621: 100.00		CHD1_HUMAN (355-1641): 0: 713: 23.83
+	Hs
		229309 FGFR3_HUMAN (168-794): 3.98e-158: 481: 25.98		SMCA5_HUMAN (626-1631): 0: 835: 27.41
+	Hs
		385581 NTRK1_HUMAN (1-796): 0: 621: 100.00		HELLS_HUMAN (683-1234): 1.22e-106: 362: 36.56
+	Rn
		88517 INSR_RAT (493-777): 7.31e-66: 241: 41.95		D3ZAP7_RAT (32-745): 1.34e-20: 101: 10.85