HitPredict

Interactor 1: NTRK1 (P04629)
High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1-transforming tyrosine kinase protein) (Tropomyosin-related kinase A) (Tyrosine kinase receptor) (Tyrosine kinase receptor A) (Trk-A) (gp140trk) (p140-TrkA)
Gene: NTRK1

Interactor 2: NSUN2 (Q08J23)
RNA cytosine C(5)-methyltransferase NSUN2 (EC 2.1.1.-) (Myc-induced SUN domain-containing protein) (Misu) (NOL1/NOP2/Sun domain family member 2) (Substrate of AIM1/Aurora kinase B) (mRNA cytosine C(5)-methyltransferase) (EC 2.1.1.-) (tRNA cytosine C(5)-methyltransferase) (EC 2.1.1.-, EC 2.1.1.203) (tRNA methyltransferase 4 homolog) (hTrm4)
Gene: NSUN2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.50	0.533

Property	Details
Experiments	25921289, 35384245
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 796 Hs			1 767
+	Hs
		507965 FGFR1_HUMAN (195-794): 0: 545: 26.34		NSUN2_HUMAN (1-767): 0: 963: 100.00
+	Hs
		609265 FGFR3_HUMAN (168-794): 3.98e-158: 481: 25.98		NSUN2_HUMAN (1-767): 0: 963: 100.00
+	Hs
		968297 ROR1_HUMAN (515-783): 1.16e-72: 257: 46.89		NSUN2_HUMAN (1-767): 0: 963: 100.00
+	Hs
		435624 IGF1R_HUMAN (493-777): 6.97e-71: 255: 42.61		NSUN2_HUMAN (1-767): 0: 963: 100.00
+	Hs
		997627 ALK_HUMAN (505-790): 8.72e-63: 231: 42.07		NSUN2_HUMAN (1-767): 0: 963: 100.00
+	Hs
		666586 LTK_HUMAN (502-790): 3.09e-60: 221: 41.64		NSUN2_HUMAN (1-767): 0: 963: 100.00
+	Hs
		384451 NTRK1_HUMAN (1-796): 0: 621: 100.00		NOP2_HUMAN (22-533): 1.53e-126: 398: 20.04