HitPredict

Interactor 1: NTRK1 (P04629)
High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1-transforming tyrosine kinase protein) (Tropomyosin-related kinase A) (Tyrosine kinase receptor) (Tyrosine kinase receptor A) (Trk-A) (gp140trk) (p140-TrkA)
Gene: NTRK1

Interactor 2: DPYL2 (Q16555)
Dihydropyrimidinase-related protein 2 (DRP-2) (Collapsin response mediator protein 2) (CRMP-2) (N2A3) (Unc-33-like phosphoprotein 2) (ULIP-2)
Gene: DPYSL2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25921289
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 796 Hs			1 572
+	Hs
		384827 NTRK1_HUMAN (1-796): 0: 621: 100.00		DPYL1_HUMAN (1-572): 0: 761: 76.22
+	Hs
		384828 NTRK1_HUMAN (1-796): 0: 621: 100.00		DPYL3_HUMAN (1-571): 0: 744: 76.71
+	Hs
		147307 NTRK1_HUMAN (1-796): 0: 621: 100.00		DPYL4_HUMAN (1-571): 0: 740: 75.66
+	Hs
		507996 FGFR1_HUMAN (195-794): 0: 545: 26.34		DPYL1_HUMAN (1-572): 0: 761: 76.22
+	Hs
		385422 NTRK1_HUMAN (1-796): 0: 621: 100.00		DPYL5_HUMAN (9-567): 0: 653: 51.34
+	Hs
		434193 RET_HUMAN (391-794): 3.5e-114: 374: 30.44		DPYL1_HUMAN (1-572): 0: 761: 76.22
+	Hs
		609501 FGFR3_HUMAN (168-794): 3.98e-158: 481: 25.98		DPYL5_HUMAN (9-567): 0: 653: 51.34
+	Hs
		609284 FGFR3_HUMAN (168-794): 3.98e-158: 481: 25.98		DPYS_HUMAN (13-528): 0: 651: 59.04
+	Hs
		384312 NTRK1_HUMAN (1-796): 0: 621: 100.00		PYR1_HUMAN (26-564): 2.07e-135: 436: 18.61
+	Hs
		435544 IGF1R_HUMAN (493-777): 6.97e-71: 255: 42.61		PYR1_HUMAN (26-564): 2.07e-135: 436: 18.61