HitPredict

Interactor 1: NTRK1 (P04629)
High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1-transforming tyrosine kinase protein) (Tropomyosin-related kinase A) (Tyrosine kinase receptor) (Tyrosine kinase receptor A) (Trk-A) (gp140trk) (p140-TrkA)
Gene: NTRK1

Interactor 2: TB10B (Q4KMP7)
TBC1 domain family member 10B (Rab27A-GAP-beta)
Gene: TBC1D10B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	25921289, 35384245
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 796 Hs			1 808
+	Hs
		508039 FGFR1_HUMAN (195-794): 0: 545: 26.34		TB10B_HUMAN (1-808): 9.38e-141: 437: 100.00
+	Hs
		385771 NTRK1_HUMAN (1-796): 0: 621: 100.00		RBGP1_HUMAN (272-805): 5.7e-105: 349: 21.44
+	Hs
		1081500 NTRK3_HUMAN (36-796): 1.63e-174: 525: 49.37		TB10B_HUMAN (1-808): 9.38e-141: 437: 100.00
+	Hs
		385345 NTRK1_HUMAN (1-796): 0: 621: 100.00		SGSM3_HUMAN (250-752): 4.13e-86: 291: 18.27
+	Hs
		232625 NTRK1_HUMAN (1-796): 0: 621: 100.00		TBCD4_HUMAN (73-712): 1.92e-80: 283: 17.35
+	Hs
		385277 NTRK1_HUMAN (1-796): 0: 621: 100.00		US6NL_HUMAN (286-797): 1.33e-79: 275: 22.82
+	Hs
		234364 FGFR4_HUMAN (140-795): 7.96e-168: 506: 25.59		EVI5_HUMAN (210-806): 2.3e-118: 378: 18.99
+	Hs
		508130 FGFR1_HUMAN (195-794): 0: 545: 26.34		US6NL_HUMAN (286-797): 1.33e-79: 275: 22.82
+	Hs
		1083876 NTRK2_HUMAN (12-796): 1.28e-176: 529: 46.72		US6NL_HUMAN (286-797): 1.33e-79: 275: 22.82
+	Hs
		1081555 NTRK3_HUMAN (36-796): 1.63e-174: 525: 49.37		US6NL_HUMAN (286-797): 1.33e-79: 275: 22.82
+	Hs
		608070 FGFR4_HUMAN (140-795): 7.96e-168: 506: 25.59		US6NL_HUMAN (286-797): 1.33e-79: 275: 22.82
+	Hs
		601560 FGFR2_HUMAN (87-794): 5.67e-159: 484: 22.55		US6NL_HUMAN (286-797): 1.33e-79: 275: 22.82
+	Hs
		968396 ROR2_HUMAN (515-783): 2.79e-66: 239: 43.91		TB10B_HUMAN (1-808): 9.38e-141: 437: 100.00
+	Hs
		872469 EPHA5_HUMAN (409-788): 2.48e-111: 365: 30.36		US6NL_HUMAN (286-797): 1.33e-79: 275: 22.82
+	Hs
		968317 ROR1_HUMAN (515-783): 1.16e-72: 257: 46.89		TBCD1_HUMAN (109-725): 7.61e-95: 323: 20.19
+	Hs
		232666 ROR1_HUMAN (515-783): 1.16e-72: 257: 46.89		TBCD4_HUMAN (73-712): 1.92e-80: 283: 17.35
+	Hs
		968329 ROR1_HUMAN (515-783): 1.16e-72: 257: 46.89		US6NL_HUMAN (286-797): 1.33e-79: 275: 22.82
+	Hs
		968449 ROR2_HUMAN (515-783): 2.79e-66: 239: 43.91		US6NL_HUMAN (286-797): 1.33e-79: 275: 22.82