HitPredict

Interactor 1: NTRK1 (P04629)
High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1-transforming tyrosine kinase protein) (Tropomyosin-related kinase A) (Tyrosine kinase receptor) (Tyrosine kinase receptor A) (Trk-A) (gp140trk) (p140-TrkA)
Gene: NTRK1

Interactor 2: GGA3 (Q9NZ52)
ADP-ribosylation factor-binding protein GGA3 (Golgi-localized, gamma ear-containing, ARF-binding protein 3)
Gene: GGA3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.60	0.561

Property	Details
Experiments	26446845
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0010008 - endosome membrane GO:0031901 - early endosome membrane GO:0032991 - protein-containing complex GO:0055038 - recycling endosome membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 796 Hs			1 723
+	Hs
		508231 FGFR1_HUMAN (195-794): 0: 545: 26.34		GGA3_HUMAN (1-723): 3.49e-148: 451: 100.00
+	Hs
		1081629 NTRK3_HUMAN (36-796): 1.63e-174: 525: 49.37		GGA3_HUMAN (1-723): 3.49e-148: 451: 100.00
+	Rn
		88616 NTRK1_RAT (1-796): 0: 592: 85.61		D3ZHG8_RAT (1-723): 6.55e-121: 378: 67.08
+	Hs
		385689 NTRK1_HUMAN (1-796): 0: 621: 100.00		GGA1_HUMAN (2-723): 1.09e-91: 301: 39.78
+	Hs
		241132 NTRK1_HUMAN (1-796): 0: 621: 100.00		TOM1_HUMAN (7-402): 8.19e-85: 278: 22.76
+	Hs
		276985 NTRK1_HUMAN (1-796): 0: 621: 100.00		STAM2_HUMAN (1-480): 4.23e-79: 264: 16.95
+	Hs
		385279 NTRK1_HUMAN (1-796): 0: 621: 100.00		STAM1_HUMAN (1-522): 4.18e-75: 254: 17.10
+	Hs
		508257 FGFR1_HUMAN (195-794): 0: 545: 26.34		GGA1_HUMAN (2-723): 1.09e-91: 301: 39.78
+	Hs
		159837 NTRK1_HUMAN (1-796): 0: 621: 100.00		HGS_HUMAN (8-709): 5.07e-58: 212: 13.37
+	Hs
		212583 NTRK1_HUMAN (1-796): 0: 621: 100.00		AP1G1_HUMAN (503-720): 2.89e-51: 193: 26.96
+	Hs
		276996 FGFR1_HUMAN (195-794): 0: 545: 26.34		STAM2_HUMAN (1-480): 4.23e-79: 264: 16.95
+	Hs
		508131 FGFR1_HUMAN (195-794): 0: 545: 26.34		STAM1_HUMAN (1-522): 4.18e-75: 254: 17.10
+	Hs
		277074 NTRK2_HUMAN (12-796): 1.28e-176: 529: 46.72		STAM2_HUMAN (1-480): 4.23e-79: 264: 16.95
+	Hs
		277073 NTRK3_HUMAN (36-796): 1.63e-174: 525: 49.37		STAM2_HUMAN (1-480): 4.23e-79: 264: 16.95
+	Hs
		1081556 NTRK3_HUMAN (36-796): 1.63e-174: 525: 49.37		STAM1_HUMAN (1-522): 4.18e-75: 254: 17.10
+	Hs
		159864 FGFR1_HUMAN (195-794): 0: 545: 26.34		HGS_HUMAN (8-709): 5.07e-58: 212: 13.37
+	Hs
		160015 NTRK2_HUMAN (12-796): 1.28e-176: 529: 46.72		HGS_HUMAN (8-709): 5.07e-58: 212: 13.37
+	Hs
		160014 NTRK3_HUMAN (36-796): 1.63e-174: 525: 49.37		HGS_HUMAN (8-709): 5.07e-58: 212: 13.37
+	Hs
		385688 NTRK1_HUMAN (1-796): 0: 621: 100.00		GGA2_HUMAN (456-721): 1.1e-25: 114: 34.83
+	Hs
		508256 FGFR1_HUMAN (195-794): 0: 545: 26.34		GGA2_HUMAN (456-721): 1.1e-25: 114: 34.83