HitPredict

Interactor 1: LMNA (P02545)
Prelamin-A/C [Cleaved into: Lamin-A/C (70 kDa lamin) (Renal carcinoma antigen NY-REN-32)]
Gene: LMNA

Interactor 2: SRSF3 (P84103)
Serine/arginine-rich splicing factor 3 (Pre-mRNA-splicing factor SRP20) (Splicing factor, arginine/serine-rich 3)
Gene: SRSF3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	25948554, 32344865
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0016607 - nuclear speck
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 664 Hs			1 164
+	Hs
		385677 LMNA_HUMAN (1-664): 1.26e-79: 267: 100.00		SRSF1_HUMAN (9-80): 1.1e-25: 100: 48.65
+	Hs
		385708 LMNA_HUMAN (1-664): 1.26e-79: 267: 100.00		SRSF5_HUMAN (10-112): 2.1e-24: 97: 44.34
+	Hs
		385707 LMNA_HUMAN (1-664): 1.26e-79: 267: 100.00		SRSF9_HUMAN (9-82): 1.92e-19: 83.2: 40.79
+	Hs
		385678 LMNA_HUMAN (1-664): 1.26e-79: 267: 100.00		SRSF4_HUMAN (11-112): 3.44e-16: 76.6: 39.22