HitPredict

Interactor 1: NTRK1 (P04629)
High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1-transforming tyrosine kinase protein) (Tropomyosin-related kinase A) (Tyrosine kinase receptor) (Tyrosine kinase receptor A) (Trk-A) (gp140trk) (p140-TrkA)
Gene: NTRK1

Interactor 2: ASAP1 (Q9ULH1)
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 (130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein) (ADP-ribosylation factor-directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (DEF-1) (Differentiation-enhancing factor 1) (PIP2-dependent ARF1 GAP)
Gene: ASAP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	25921289
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~PK_Tyr_Ser-Thr, PK_Tyr_Ser-Thr~SH3_9
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 796 Hs			1 1129
+	Hs
		508262 FGFR1_HUMAN (195-794): 0: 545: 26.34		ASAP1_HUMAN (17-1129): 0: 831: 100.00
+	Hs
		608185 FGFR4_HUMAN (140-795): 7.96e-168: 506: 25.59		ASAP1_HUMAN (17-1129): 0: 831: 100.00
+	Hs
		195775 NTRK1_HUMAN (1-796): 0: 621: 100.00		ASAP2_HUMAN (21-967): 0: 647: 55.31
+	Hs
		385190 NTRK1_HUMAN (1-796): 0: 621: 100.00		DP13B_HUMAN (45-453): 1.01e-98: 329: 16.03
+	Hs
		385693 NTRK1_HUMAN (1-796): 0: 621: 100.00		DP13A_HUMAN (45-460): 7.54e-92: 312: 16.24
+	Hs
		508261 FGFR1_HUMAN (195-794): 0: 545: 26.34		DP13A_HUMAN (45-460): 7.54e-92: 312: 16.24
+	Hs
		385363 NTRK1_HUMAN (1-796): 0: 621: 100.00		AGAP3_HUMAN (361-662): 1.44e-59: 223: 27.97
+	Hs
		385364 NTRK1_HUMAN (1-796): 0: 621: 100.00		ARAP1_HUMAN (368-620): 3.83e-58: 222: 24.90
+	Hs
		1083906 NTRK2_HUMAN (12-796): 1.28e-176: 529: 46.72		DP13A_HUMAN (45-460): 7.54e-92: 312: 16.24
+	Hs
		1081642 NTRK3_HUMAN (36-796): 1.63e-174: 525: 49.37		DP13A_HUMAN (45-460): 7.54e-92: 312: 16.24
+	Hs
		385239 NTRK1_HUMAN (1-796): 0: 621: 100.00		ARAP3_HUMAN (368-605): 4.78e-56: 215: 27.46
+	Hs
		608050 FGFR4_HUMAN (140-795): 7.96e-168: 506: 25.59		DP13B_HUMAN (45-453): 1.01e-98: 329: 16.03
+	Hs
		608182 FGFR4_HUMAN (140-795): 7.96e-168: 506: 25.59		DP13A_HUMAN (45-460): 7.54e-92: 312: 16.24
+	Hs
		609490 FGFR3_HUMAN (168-794): 3.98e-158: 481: 25.98		ARAP1_HUMAN (368-620): 3.83e-58: 222: 24.90
+	Hs
		872503 EPHA5_HUMAN (409-788): 2.48e-111: 365: 30.36		DP13A_HUMAN (45-460): 7.54e-92: 312: 16.24
+	Hs
		508123 FGFR1_HUMAN (195-794): 0: 545: 26.34		SMAP2_HUMAN (436-549): 5.1e-16: 84: 36.21
+	Hs
		608061 FGFR4_HUMAN (140-795): 7.96e-168: 506: 25.59		SMAP2_HUMAN (436-549): 5.1e-16: 84: 36.21
+	Hs
		601555 FGFR2_HUMAN (87-794): 5.67e-159: 484: 22.55		SMAP2_HUMAN (436-549): 5.1e-16: 84: 36.21
+	Hs
		434250 RET_HUMAN (391-794): 3.5e-114: 374: 30.44		SMAP2_HUMAN (436-549): 5.1e-16: 84: 36.21
+	Hs
		872465 EPHA5_HUMAN (409-788): 2.48e-111: 365: 30.36		SMAP2_HUMAN (436-549): 5.1e-16: 84: 36.21