Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53
Interactor 2: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.99 | 1.00 | 0.995 |
The method score is based on:
Property | Details |
---|---|
Experiments | 19339993, 21231916, 8035799, 22522597, 27462439, 25603536, 24374182, 14580323, 29549180, 17135243, 30503669, 11948396, 28205554, 31152661, 31182485, 32904724, 32807901, 36358651, 36352191, 19011633 and 26 others
more... |
Identification Methods | pull down, biochemical, affinity chromatography technology, x-ray crystallography, fluorescent resonance energy transfer, two hybrid, tandem affinity purification, ubiquitin reconstruction, cosedimentation in solution, nuclear magnetic resonance and 10 others
more... |
Interaction Type | direct interaction, association, physical association, phosphorylation reaction |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | P53~P53, P53~P53_tetramer, P53_TAD~TAD2, P53_tetramer~P53_tetramer |
Common GO terms | GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000423 - mitophagy GO:0000785 - chromatin GO:0000976 - transcription cis-regulatory region binding GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding and 168 others more... |
Homologous interactions | 14 |
Homologous interactions
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024